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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPO
All Species:
2.12
Human Site:
T881
Identified Species:
5.83
UniProt:
P07202
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07202
NP_000538.3
933
102963
T881
T
R
T
G
T
K
S
T
L
P
I
S
E
T
G
Chimpanzee
Pan troglodytes
XP_523809
715
81024
K664
V
F
T
K
R
Q
R
K
A
L
S
R
I
S
L
Rhesus Macaque
Macaca mulatta
XP_001117795
995
110682
D881
P
V
G
H
L
H
H
D
C
S
F
A
A
L
Q
Dog
Lupus familis
XP_852445
734
82942
L683
S
S
Q
Q
Q
Q
A
L
A
R
I
S
L
P
R
Cat
Felis silvestris
Mouse
Mus musculus
P35419
914
101324
T862
W
I
V
I
C
R
W
T
H
A
D
K
K
A
T
Rat
Rattus norvegicus
P14650
914
101442
T862
W
T
V
I
C
R
W
T
H
A
D
K
K
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511489
1069
118629
G923
T
Y
S
V
P
G
V
G
S
P
R
L
E
A
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081848
713
80479
A662
V
F
T
N
E
Q
R
A
S
I
E
R
V
T
L
Zebra Danio
Brachydanio rerio
XP_697836
627
70897
R576
Q
I
V
D
I
S
C
R
K
Q
G
K
D
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.3
84.3
36
N.A.
73.4
74
N.A.
57.9
N.A.
32.7
38.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
48.6
86.3
50.3
N.A.
83.2
83.5
N.A.
69.4
N.A.
47.2
49.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
13.3
N.A.
6.6
6.6
N.A.
26.6
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
6.6
33.3
N.A.
20
26.6
N.A.
33.3
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
12
23
23
0
12
12
23
0
% A
% Cys:
0
0
0
0
23
0
12
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
12
0
0
23
0
12
0
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
12
0
23
0
0
% E
% Phe:
0
23
0
0
0
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
0
0
12
12
0
12
0
12
0
0
12
0
0
0
23
% G
% His:
0
0
0
12
0
12
12
0
23
0
0
0
0
0
0
% H
% Ile:
0
23
0
23
12
0
0
0
0
12
23
0
12
0
0
% I
% Lys:
0
0
0
12
0
12
0
12
12
0
0
34
23
0
0
% K
% Leu:
0
0
0
0
12
0
0
12
12
12
0
12
12
12
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
12
0
0
0
0
23
0
0
0
12
0
% P
% Gln:
12
0
12
12
12
34
0
0
0
12
0
0
0
0
12
% Q
% Arg:
0
12
0
0
12
23
23
12
0
12
12
23
0
0
12
% R
% Ser:
12
12
12
0
0
12
12
0
23
12
12
23
0
23
0
% S
% Thr:
23
12
34
0
12
0
0
34
0
0
0
0
0
34
23
% T
% Val:
23
12
34
12
0
0
12
0
0
0
0
0
12
0
12
% V
% Trp:
23
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _