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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROS1
All Species:
23.33
Human Site:
S394
Identified Species:
51.33
UniProt:
P07225
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07225
NP_000304.2
676
75123
S394
S
V
E
E
L
E
H
S
I
S
I
K
I
A
K
Chimpanzee
Pan troglodytes
Q95ND7
461
51746
T205
D
V
D
Y
V
N
S
T
E
A
E
T
I
L
D
Rhesus Macaque
Macaca mulatta
Q28520
649
72384
S367
S
V
E
E
L
E
H
S
I
S
I
K
I
A
K
Dog
Lupus familis
XP_535708
677
74556
S394
S
V
E
E
L
E
Y
S
I
S
I
K
I
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q08761
675
74916
S394
S
V
E
E
L
D
D
S
V
S
I
K
I
A
K
Rat
Rattus norvegicus
P53813
675
74608
S394
S
V
E
E
L
D
D
S
V
S
I
K
I
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514997
658
74086
I380
S
V
E
E
L
E
G
I
I
S
V
K
I
A
K
Chicken
Gallus gallus
P25155
475
53123
E220
E
V
F
T
T
T
T
E
S
P
T
P
P
P
R
Frog
Xenopus laevis
NP_001086582
669
75214
N385
S
V
E
E
L
D
R
N
L
V
I
K
V
N
K
Zebra Danio
Brachydanio rerio
NP_001070791
673
74054
S394
S
V
E
E
L
S
G
S
I
S
V
K
I
S
K
Tiger Blowfish
Takifugu rubipres
NP_001027783
475
53756
I220
E
M
S
T
M
T
R
I
V
N
G
E
D
C
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.2
92
79.4
N.A.
79.5
80
N.A.
62.5
23.6
44.6
51.1
22
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
36.6
94.8
87.8
N.A.
89.3
89.3
N.A.
77
36.5
63.1
68.7
36
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
80
80
N.A.
80
6.6
53.3
73.3
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
93.3
93.3
N.A.
86.6
13.3
80
86.6
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
55
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
0
10
0
0
28
19
0
0
0
0
0
10
0
10
% D
% Glu:
19
0
73
73
0
37
0
10
10
0
10
10
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
19
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
19
46
0
55
0
73
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
73
% K
% Leu:
0
0
0
0
73
0
0
0
10
0
0
0
0
10
0
% L
% Met:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
10
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
10
10
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
10
% R
% Ser:
73
0
10
0
0
10
10
55
10
64
0
0
0
10
0
% S
% Thr:
0
0
0
19
10
19
10
10
0
0
10
10
0
0
0
% T
% Val:
0
91
0
0
10
0
0
0
28
10
19
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _