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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PROS1 All Species: 20.91
Human Site: S483 Identified Species: 46
UniProt: P07225 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07225 NP_000304.2 676 75123 S483 L V T V E K G S Y Y P G S G I
Chimpanzee Pan troglodytes Q95ND7 461 51746 G280 V K I T V V A G E H N I E E T
Rhesus Macaque Macaca mulatta Q28520 649 72384 S456 L V T V E K G S Y Y P G S G I
Dog Lupus familis XP_535708 677 74556 Y484 V T V E K G S Y Y P G S G V A
Cat Felis silvestris
Mouse Mus musculus Q08761 675 74916 S483 F L N V E K G S Y Y P G S G I
Rat Rattus norvegicus P53813 675 74608 S483 F L T V E K G S Y Y P G S G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514997 658 74086 S469 L V T V E K G S Y Y P A T G V
Chicken Gallus gallus P25155 475 53123 V294 S K E I K V V V G E V D R E K
Frog Xenopus laevis NP_001086582 669 75214 P476 A G R G S F F P G R G F A L F
Zebra Danio Brachydanio rerio NP_001070791 673 74054 S482 Y V H V E K G S F F S G G G H
Tiger Blowfish Takifugu rubipres NP_001027783 475 53756 L294 M Y E V E T I L A H Y N Y K P
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.2 92 79.4 N.A. 79.5 80 N.A. 62.5 23.6 44.6 51.1 22 N.A. N.A. N.A. N.A.
Protein Similarity: 100 36.6 94.8 87.8 N.A. 89.3 89.3 N.A. 77 36.5 63.1 68.7 36 N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 6.6 N.A. 80 86.6 N.A. 80 0 0 53.3 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 20 N.A. 86.6 93.3 N.A. 93.3 13.3 6.6 66.6 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 10 0 10 0 0 10 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 19 10 64 0 0 0 10 10 0 0 10 19 0 % E
% Phe: 19 0 0 0 0 10 10 0 10 10 0 10 0 0 10 % F
% Gly: 0 10 0 10 0 10 55 10 19 0 19 46 19 55 0 % G
% His: 0 0 10 0 0 0 0 0 0 19 0 0 0 0 10 % H
% Ile: 0 0 10 10 0 0 10 0 0 0 0 10 0 0 37 % I
% Lys: 0 19 0 0 19 55 0 0 0 0 0 0 0 10 10 % K
% Leu: 28 19 0 0 0 0 0 10 0 0 0 0 0 10 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 10 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 10 46 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 10 0 0 10 0 0 % R
% Ser: 10 0 0 0 10 0 10 55 0 0 10 10 37 0 0 % S
% Thr: 0 10 37 10 0 10 0 0 0 0 0 0 10 0 10 % T
% Val: 19 37 10 64 10 19 10 10 0 0 10 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 10 0 0 0 0 0 10 55 46 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _