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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P4HB
All Species:
28.48
Human Site:
S166
Identified Species:
48.21
UniProt:
P07237
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07237
NP_000909.2
508
57116
S166
G
F
F
K
D
V
E
S
D
S
A
K
Q
F
L
Chimpanzee
Pan troglodytes
XP_001164396
508
57114
S166
G
F
F
K
D
V
E
S
D
S
A
K
Q
F
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540488
510
57398
S168
G
F
F
K
D
V
E
S
D
F
A
K
Q
F
L
Cat
Felis silvestris
Mouse
Mus musculus
P09103
509
57125
S168
G
F
F
K
D
V
E
S
D
S
A
K
Q
F
L
Rat
Rattus norvegicus
P04785
509
56933
S168
G
F
F
K
D
A
G
S
D
S
A
K
Q
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517226
512
56706
S170
G
F
F
K
D
A
G
S
E
P
A
K
Q
F
L
Chicken
Gallus gallus
P12244
508
56874
G165
I
G
F
F
K
D
P
G
S
D
S
A
R
Q
F
Frog
Xenopus laevis
NP_001079815
505
56621
S166
G
F
F
K
D
P
E
S
E
L
A
K
V
F
L
Zebra Danio
Brachydanio rerio
NP_998529
509
56615
S164
G
F
F
K
D
V
E
S
E
D
S
K
A
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
A169
K
D
L
E
S
E
E
A
K
T
F
T
K
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17770
493
55134
A165
K
D
T
T
S
D
D
A
K
T
F
L
E
V
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
G177
G
I
F
A
E
F
S
G
T
E
F
T
N
F
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI01
501
55583
G173
G
I
F
P
K
L
S
G
S
E
F
D
S
F
M
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
F173
S
G
K
I
D
A
D
F
N
A
T
F
Y
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
93.1
N.A.
93.7
93.9
N.A.
88.4
83.8
76.3
72.5
N.A.
54.1
N.A.
56.5
N.A.
Protein Similarity:
100
99.8
N.A.
96
N.A.
96.2
96.2
N.A.
94.3
91.7
86
85.6
N.A.
71.6
N.A.
74.2
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
86.6
N.A.
73.3
6.6
73.3
66.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
86.6
N.A.
80
20
80
86.6
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
36.4
N.A.
36.4
30.2
N.A.
Protein Similarity:
N.A.
54.9
N.A.
58.2
49.6
N.A.
P-Site Identity:
N.A.
20
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
22
0
15
0
8
50
8
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
65
15
15
0
36
15
0
8
0
0
0
% D
% Glu:
0
0
0
8
8
8
50
0
22
15
0
0
8
0
0
% E
% Phe:
0
58
79
8
0
8
0
8
0
8
29
8
0
72
8
% F
% Gly:
72
15
0
0
0
0
15
22
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
15
0
8
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
15
0
8
58
15
0
0
0
15
0
0
58
8
0
0
% K
% Leu:
0
0
8
0
0
8
0
0
0
8
0
8
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
22
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
8
0
8
8
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
43
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
0
0
15
0
15
58
15
29
15
0
8
8
0
% S
% Thr:
0
0
8
8
0
0
0
0
8
15
8
15
0
0
0
% T
% Val:
0
0
0
0
0
36
0
0
0
0
0
0
8
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _