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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P4HB
All Species:
43.03
Human Site:
S188
Identified Species:
72.82
UniProt:
P07237
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07237
NP_000909.2
508
57116
S188
D
I
P
F
G
I
T
S
N
S
D
V
F
S
K
Chimpanzee
Pan troglodytes
XP_001164396
508
57114
S188
D
I
P
F
G
I
T
S
N
S
D
V
F
S
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540488
510
57398
S190
D
I
P
F
G
I
T
S
N
S
D
V
F
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P09103
509
57125
S190
D
I
P
F
G
I
T
S
N
S
G
V
F
S
K
Rat
Rattus norvegicus
P04785
509
56933
S190
D
I
P
F
G
I
T
S
N
S
D
V
F
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517226
512
56706
S192
D
I
P
F
G
I
T
S
G
G
E
V
F
A
K
Chicken
Gallus gallus
P12244
508
56874
S188
D
V
P
F
G
I
N
S
N
S
D
V
Y
S
K
Frog
Xenopus laevis
NP_001079815
505
56621
S188
D
I
P
F
G
I
T
S
S
D
A
A
F
S
K
Zebra Danio
Brachydanio rerio
NP_998529
509
56615
S186
D
I
P
F
G
I
T
S
D
D
S
V
F
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
S188
S
F
V
F
G
V
S
S
N
A
D
V
I
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17770
493
55134
T184
D
V
P
F
G
I
S
T
E
D
A
V
K
S
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
L200
D
Y
D
F
G
H
T
L
H
A
N
H
L
P
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI01
501
55583
S196
E
L
D
F
A
H
T
S
D
A
K
L
L
P
R
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
E194
D
Y
D
F
V
S
A
E
N
A
D
D
D
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
93.1
N.A.
93.7
93.9
N.A.
88.4
83.8
76.3
72.5
N.A.
54.1
N.A.
56.5
N.A.
Protein Similarity:
100
99.8
N.A.
96
N.A.
96.2
96.2
N.A.
94.3
91.7
86
85.6
N.A.
71.6
N.A.
74.2
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
73.3
80
73.3
73.3
N.A.
46.6
N.A.
46.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
86.6
93.3
80
86.6
N.A.
73.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
36.4
N.A.
36.4
30.2
N.A.
Protein Similarity:
N.A.
54.9
N.A.
58.2
49.6
N.A.
P-Site Identity:
N.A.
26.6
N.A.
20
33.3
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
60
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
0
29
15
8
0
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
86
0
22
0
0
0
0
0
15
22
50
8
8
0
0
% D
% Glu:
8
0
0
0
0
0
0
8
8
0
8
0
0
0
8
% E
% Phe:
0
8
0
100
0
0
0
0
0
0
0
0
58
8
0
% F
% Gly:
0
0
0
0
86
0
0
0
8
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
15
0
0
8
0
0
8
0
0
0
% H
% Ile:
0
58
0
0
0
72
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
79
% K
% Leu:
0
8
0
0
0
0
0
8
0
0
0
8
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
58
0
8
0
0
0
0
% N
% Pro:
0
0
72
0
0
0
0
0
0
0
0
0
0
15
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% R
% Ser:
8
0
0
0
0
8
15
79
8
43
8
0
0
58
0
% S
% Thr:
0
0
0
0
0
0
72
8
0
0
0
0
0
0
0
% T
% Val:
0
15
8
0
8
8
0
0
0
0
0
72
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _