KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P4HB
All Species:
15.15
Human Site:
S281
Identified Species:
25.64
UniProt:
P07237
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07237
NP_000909.2
508
57116
S281
N
F
K
T
A
A
E
S
F
K
G
K
I
L
F
Chimpanzee
Pan troglodytes
XP_001164396
508
57114
S281
N
F
K
T
A
A
E
S
F
K
G
K
I
L
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540488
510
57398
R283
N
F
K
K
A
A
E
R
F
K
G
K
I
L
F
Cat
Felis silvestris
Mouse
Mus musculus
P09103
509
57125
G283
S
F
K
R
A
A
E
G
F
K
G
K
I
L
F
Rat
Rattus norvegicus
P04785
509
56933
G283
N
F
K
K
A
A
E
G
F
K
G
K
I
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517226
512
56706
S285
N
F
K
K
A
A
G
S
F
K
G
K
I
L
F
Chicken
Gallus gallus
P12244
508
56874
G281
N
L
K
K
A
A
D
G
F
K
G
K
I
L
F
Frog
Xenopus laevis
NP_001079815
505
56621
S281
N
F
K
K
A
A
E
S
F
K
G
K
I
L
F
Zebra Danio
Brachydanio rerio
NP_998529
509
56615
G279
Q
F
K
K
A
A
E
G
F
K
G
K
I
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
K281
P
L
K
E
I
A
K
K
Y
R
D
D
I
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17770
493
55134
Q277
E
F
K
N
A
A
K
Q
F
K
G
K
V
L
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
A294
S
F
K
S
A
Y
S
A
A
A
E
E
F
K
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI01
501
55583
S294
K
Y
R
E
V
A
T
S
N
K
G
Q
G
L
S
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
A281
K
P
L
F
T
E
L
A
K
K
N
R
G
L
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
93.1
N.A.
93.7
93.9
N.A.
88.4
83.8
76.3
72.5
N.A.
54.1
N.A.
56.5
N.A.
Protein Similarity:
100
99.8
N.A.
96
N.A.
96.2
96.2
N.A.
94.3
91.7
86
85.6
N.A.
71.6
N.A.
74.2
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
86.6
N.A.
86.6
73.3
93.3
80
N.A.
33.3
N.A.
66.6
N.A.
P-Site Similarity:
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
86.6
80
93.3
80
N.A.
53.3
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
36.4
N.A.
36.4
30.2
N.A.
Protein Similarity:
N.A.
54.9
N.A.
58.2
49.6
N.A.
P-Site Identity:
N.A.
20
N.A.
33.3
13.3
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
79
86
0
15
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
8
8
0
0
8
% D
% Glu:
8
0
0
15
0
8
50
0
0
0
8
8
0
0
0
% E
% Phe:
0
72
0
8
0
0
0
0
72
0
0
0
8
0
79
% F
% Gly:
0
0
0
0
0
0
8
29
0
0
79
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
72
0
0
% I
% Lys:
15
0
86
43
0
0
15
8
8
86
0
72
0
8
0
% K
% Leu:
0
15
8
0
0
0
8
0
0
0
0
0
0
93
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
50
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
8
0
0
0
8
0
8
0
8
0
0
0
% R
% Ser:
15
0
0
8
0
0
8
36
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
15
8
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _