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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P4HB
All Species:
30.61
Human Site:
S472
Identified Species:
51.79
UniProt:
P07237
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07237
NP_000909.2
508
57116
S472
G
F
K
K
F
L
E
S
G
G
Q
D
G
A
G
Chimpanzee
Pan troglodytes
XP_001164396
508
57114
S472
G
F
K
K
F
L
E
S
G
G
Q
D
G
A
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540488
510
57398
S474
G
F
K
K
F
L
E
S
G
G
Q
D
G
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P09103
509
57125
S474
G
F
K
K
F
L
E
S
G
G
Q
D
G
A
G
Rat
Rattus norvegicus
P04785
509
56933
S474
G
F
K
K
F
L
E
S
G
G
Q
D
G
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517226
512
56706
S476
G
F
T
K
F
L
E
S
G
G
Q
D
G
A
A
Chicken
Gallus gallus
P12244
508
56874
S473
G
Y
K
K
F
L
E
S
G
G
Q
D
G
Y
G
Frog
Xenopus laevis
NP_001079815
505
56621
G472
F
S
K
F
L
E
S
G
G
Q
D
G
A
A
D
Zebra Danio
Brachydanio rerio
NP_998529
509
56615
S470
G
F
T
K
F
L
E
S
G
G
K
E
G
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
N472
F
V
K
F
L
D
A
N
G
E
V
A
D
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17770
493
55134
N468
F
T
K
F
L
E
T
N
G
K
E
G
A
G
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
S483
I
V
D
F
I
K
K
S
K
E
T
A
A
P
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI01
501
55583
K479
D
F
I
S
F
V
D
K
N
K
D
T
V
G
E
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
E482
S
L
F
D
F
I
K
E
N
G
H
F
D
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
93.1
N.A.
93.7
93.9
N.A.
88.4
83.8
76.3
72.5
N.A.
54.1
N.A.
56.5
N.A.
Protein Similarity:
100
99.8
N.A.
96
N.A.
96.2
96.2
N.A.
94.3
91.7
86
85.6
N.A.
71.6
N.A.
74.2
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
86.6
20
66.6
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
93.3
20
80
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
36.4
N.A.
36.4
30.2
N.A.
Protein Similarity:
N.A.
54.9
N.A.
58.2
49.6
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
15
22
50
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
8
8
0
0
0
15
50
15
0
15
% D
% Glu:
0
0
0
0
0
15
58
8
0
15
8
8
0
0
15
% E
% Phe:
22
58
8
29
72
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
58
0
0
0
0
0
0
8
79
65
0
15
58
22
43
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% H
% Ile:
8
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
65
58
0
8
15
8
8
15
8
0
0
0
0
% K
% Leu:
0
8
0
0
22
58
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
15
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
50
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
8
0
0
8
65
0
0
0
0
0
8
0
% S
% Thr:
0
8
15
0
0
0
8
0
0
0
8
8
0
0
0
% T
% Val:
0
15
0
0
0
8
0
0
0
0
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _