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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P4HB
All Species:
6.36
Human Site:
T277
Identified Species:
10.77
UniProt:
P07237
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07237
NP_000909.2
508
57116
T277
G
K
L
S
N
F
K
T
A
A
E
S
F
K
G
Chimpanzee
Pan troglodytes
XP_001164396
508
57114
T277
S
K
L
S
N
F
K
T
A
A
E
S
F
K
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540488
510
57398
K279
S
K
L
S
N
F
K
K
A
A
E
R
F
K
G
Cat
Felis silvestris
Mouse
Mus musculus
P09103
509
57125
R279
G
K
L
S
S
F
K
R
A
A
E
G
F
K
G
Rat
Rattus norvegicus
P04785
509
56933
K279
G
K
L
S
N
F
K
K
A
A
E
G
F
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517226
512
56706
K281
G
K
L
N
N
F
K
K
A
A
G
S
F
K
G
Chicken
Gallus gallus
P12244
508
56874
K277
G
K
L
S
N
L
K
K
A
A
D
G
F
K
G
Frog
Xenopus laevis
NP_001079815
505
56621
K277
D
K
L
E
N
F
K
K
A
A
E
S
F
K
G
Zebra Danio
Brachydanio rerio
NP_998529
509
56615
K275
D
K
M
D
Q
F
K
K
A
A
E
G
F
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
E277
K
Y
V
D
P
L
K
E
I
A
K
K
Y
R
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17770
493
55134
N273
K
L
E
Q
E
F
K
N
A
A
K
Q
F
K
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
S290
G
P
F
D
S
F
K
S
A
Y
S
A
A
A
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI01
501
55583
E290
S
L
K
S
K
Y
R
E
V
A
T
S
N
K
G
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
F277
L
E
E
Y
K
P
L
F
T
E
L
A
K
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
93.1
N.A.
93.7
93.9
N.A.
88.4
83.8
76.3
72.5
N.A.
54.1
N.A.
56.5
N.A.
Protein Similarity:
100
99.8
N.A.
96
N.A.
96.2
96.2
N.A.
94.3
91.7
86
85.6
N.A.
71.6
N.A.
74.2
N.A.
P-Site Identity:
100
93.3
N.A.
80
N.A.
80
86.6
N.A.
80
73.3
80
60
N.A.
13.3
N.A.
46.6
N.A.
P-Site Similarity:
100
93.3
N.A.
80
N.A.
86.6
86.6
N.A.
86.6
80
80
66.6
N.A.
40
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
36.4
N.A.
36.4
30.2
N.A.
Protein Similarity:
N.A.
54.9
N.A.
58.2
49.6
N.A.
P-Site Identity:
N.A.
26.6
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
79
86
0
15
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
22
0
0
0
0
0
0
8
0
0
0
8
% D
% Glu:
0
8
15
8
8
0
0
15
0
8
50
0
0
0
8
% E
% Phe:
0
0
8
0
0
72
0
8
0
0
0
0
72
0
0
% F
% Gly:
43
0
0
0
0
0
0
0
0
0
8
29
0
0
79
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
15
65
8
0
15
0
86
43
0
0
15
8
8
86
0
% K
% Leu:
8
15
58
0
0
15
8
0
0
0
8
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
50
0
0
8
0
0
0
0
8
0
8
% N
% Pro:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
8
0
0
0
8
0
8
0
% R
% Ser:
22
0
0
50
15
0
0
8
0
0
8
36
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
15
8
0
8
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
8
0
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _