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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSF1R
All Species:
11.21
Human Site:
S178
Identified Species:
24.67
UniProt:
P07333
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07333
NP_005202.2
972
107984
S178
Q
S
Q
D
Y
Q
C
S
A
L
M
G
G
R
K
Chimpanzee
Pan troglodytes
XP_517285
1073
120068
C284
K
R
A
Y
H
R
L
C
L
H
C
S
V
D
Q
Rhesus Macaque
Macaca mulatta
XP_001107833
976
108270
S178
Q
G
Q
D
Y
Q
C
S
A
L
M
G
S
R
K
Dog
Lupus familis
XP_546306
967
107148
S178
E
T
Q
G
Y
Q
C
S
A
R
V
G
G
R
T
Cat
Felis silvestris
Mouse
Mus musculus
P09581
977
109161
K178
D
S
N
T
Y
V
C
K
T
M
V
N
G
R
E
Rat
Rattus norvegicus
Q00495
978
109246
K178
D
S
N
T
Y
V
C
K
T
M
V
N
G
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506832
966
107509
S171
I
I
K
S
V
Q
R
S
Y
N
K
V
C
F
Q
Chicken
Gallus gallus
Q08156
960
107293
S168
I
I
K
N
V
Q
R
S
F
K
G
C
Y
Q
C
Frog
Xenopus laevis
Q91909
954
106841
Q172
G
I
T
I
K
T
V
Q
L
A
F
D
S
C
Y
Zebra Danio
Brachydanio rerio
Q9I8N6
977
110169
R169
M
N
I
T
Y
D
P
R
K
G
V
L
I
R
N
Tiger Blowfish
Takifugu rubipres
P79750
975
110895
S182
L
I
R
S
L
Q
P
S
F
N
A
D
Y
V
C
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
95.6
84.3
N.A.
75.1
74.7
N.A.
40.7
39.2
39.2
45
43.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
52.7
97.2
88.7
N.A.
83.2
82.8
N.A.
56.3
56.3
56.3
61.1
60.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
86.6
60
N.A.
33.3
33.3
N.A.
13.3
13.3
0
13.3
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
86.6
80
N.A.
53.3
53.3
N.A.
26.6
33.3
0
26.6
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
28
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
46
10
0
0
10
10
10
10
19
% C
% Asp:
19
0
0
19
0
10
0
0
0
0
0
19
0
10
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% E
% Phe:
0
0
0
0
0
0
0
0
19
0
10
0
0
10
0
% F
% Gly:
10
10
0
10
0
0
0
0
0
10
10
28
37
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
19
37
10
10
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
10
0
19
0
10
0
0
19
10
10
10
0
0
0
19
% K
% Leu:
10
0
0
0
10
0
10
0
19
19
0
10
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
19
19
0
0
0
0
% M
% Asn:
0
10
19
10
0
0
0
0
0
19
0
19
0
0
10
% N
% Pro:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% P
% Gln:
19
0
28
0
0
55
0
10
0
0
0
0
0
10
19
% Q
% Arg:
0
10
10
0
0
10
19
10
0
10
0
0
0
55
0
% R
% Ser:
0
28
0
19
0
0
0
55
0
0
0
10
19
0
0
% S
% Thr:
0
10
10
28
0
10
0
0
19
0
0
0
0
0
10
% T
% Val:
0
0
0
0
19
19
10
0
0
0
37
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
55
0
0
0
10
0
0
0
19
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _