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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C8A
All Species:
16.36
Human Site:
S427
Identified Species:
40
UniProt:
P07357
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07357
NP_000553.1
584
65163
S427
I
S
R
V
R
G
G
S
S
G
W
S
G
G
L
Chimpanzee
Pan troglodytes
XP_513435
584
65164
S427
I
S
R
V
R
G
G
S
S
G
W
S
G
G
L
Rhesus Macaque
Macaca mulatta
XP_001114403
584
65403
S427
I
S
R
V
R
G
G
S
S
G
W
S
G
G
L
Dog
Lupus familis
XP_536695
589
66184
G430
D
I
I
S
L
V
R
G
G
S
S
G
W
G
A
Cat
Felis silvestris
Mouse
Mus musculus
NP_666260
587
66062
S427
I
S
R
V
Q
G
G
S
S
V
W
G
S
V
L
Rat
Rattus norvegicus
NP_001100140
587
66255
S427
I
S
R
V
Q
G
G
S
S
R
W
S
T
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519289
517
57291
D385
L
K
E
L
G
V
E
D
V
I
S
R
V
R
G
Chicken
Gallus gallus
XP_426667
603
67707
R441
V
M
E
D
I
I
V
R
I
K
G
G
D
T
S
Frog
Xenopus laevis
NP_001085549
589
66857
K429
K
D
V
V
T
Y
V
K
G
G
D
T
G
S
A
Zebra Danio
Brachydanio rerio
NP_001003496
478
53142
K345
K
D
W
G
K
S
L
K
Y
N
P
A
L
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
94.5
77.4
N.A.
72.2
73.7
N.A.
42.6
52.9
50
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
96.4
85.5
N.A.
83.3
85
N.A.
60.7
67.8
68.4
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
66.6
80
N.A.
0
0
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
73.3
86.6
N.A.
13.3
6.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
20
0
10
0
0
0
10
0
0
10
0
10
0
0
% D
% Glu:
0
0
20
0
0
0
10
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
50
50
10
20
40
10
30
40
50
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
10
10
0
10
10
0
0
10
10
0
0
0
10
0
% I
% Lys:
20
10
0
0
10
0
0
20
0
10
0
0
0
0
0
% K
% Leu:
10
0
0
10
10
0
10
0
0
0
0
0
10
0
50
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
50
0
30
0
10
10
0
10
0
10
0
10
0
% R
% Ser:
0
50
0
10
0
10
0
50
50
10
20
40
10
10
10
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
10
10
10
0
% T
% Val:
10
0
10
60
0
20
20
0
10
10
0
0
10
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
50
0
10
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _