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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C8A All Species: 29.09
Human Site: Y199 Identified Species: 71.11
UniProt: P07357 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07357 NP_000553.1 584 65163 Y199 S T C E R L Y Y G D D E K Y F
Chimpanzee Pan troglodytes XP_513435 584 65164 Y199 S T C E R L Y Y G D D E K Y F
Rhesus Macaque Macaca mulatta XP_001114403 584 65403 Y199 P T C E R L Y Y G D D E K Y F
Dog Lupus familis XP_536695 589 66184 Y202 P T C E R L Y Y G E D E K Y F
Cat Felis silvestris
Mouse Mus musculus NP_666260 587 66062 Y199 P T C E R L Y Y G E D E K Y F
Rat Rattus norvegicus NP_001100140 587 66255 Y199 P T C E R L Y Y G E D E K Y F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519289 517 57291 C161 E F R Y D P A C E R L H Y G D
Chicken Gallus gallus XP_426667 603 67707 Y213 A A C E R L Y Y G D D E K Y L
Frog Xenopus laevis NP_001085549 589 66857 Y201 P V C E Q L Y Y S D D E K Y F
Zebra Danio Brachydanio rerio NP_001003496 478 53142 A121 F L S F Q I M A Q A S T E E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 94.5 77.4 N.A. 72.2 73.7 N.A. 42.6 52.9 50 36.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 96.4 85.5 N.A. 83.3 85 N.A. 60.7 67.8 68.4 53.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 0 80 73.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 0 86.6 80 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 10 10 0 10 0 0 0 0 0 % A
% Cys: 0 0 80 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 50 80 0 0 0 10 % D
% Glu: 10 0 0 80 0 0 0 0 10 30 0 80 10 10 0 % E
% Phe: 10 10 0 10 0 0 0 0 0 0 0 0 0 0 70 % F
% Gly: 0 0 0 0 0 0 0 0 70 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % K
% Leu: 0 10 0 0 0 80 0 0 0 0 10 0 0 0 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 20 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 70 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 20 0 10 0 0 0 0 0 10 0 10 0 0 0 10 % S
% Thr: 0 60 0 0 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 80 80 0 0 0 0 10 80 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _