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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C8B
All Species:
17.88
Human Site:
S118
Identified Species:
49.17
UniProt:
P07358
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07358
NP_000057.1
591
67047
S118
V
T
N
R
P
C
R
S
Q
V
R
C
E
G
F
Chimpanzee
Pan troglodytes
P61134
934
104929
I135
I
P
S
K
L
C
K
I
E
E
A
D
C
K
N
Rhesus Macaque
Macaca mulatta
XP_001114456
591
66882
T118
V
T
N
R
P
C
R
T
Q
V
R
C
E
G
F
Dog
Lupus familis
XP_536694
590
66980
S118
V
T
S
R
P
C
R
S
Q
V
R
C
E
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH35
589
66211
S117
V
T
N
Q
P
C
R
S
Q
V
R
C
E
G
F
Rat
Rattus norvegicus
P55314
589
66648
S117
V
T
N
R
A
C
R
S
Q
V
R
C
E
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511856
285
31949
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001332819
562
62810
L110
G
R
C
V
L
E
N
L
R
C
N
G
D
D
D
Tiger Blowfish
Takifugu rubipres
P79755
586
65179
K114
S
C
I
K
L
R
L
K
C
N
G
D
Y
D
C
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.4
95.5
84.9
N.A.
75.3
78.6
N.A.
28
N.A.
N.A.
46.7
30.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
33.8
97.1
89.6
N.A.
84
86.8
N.A.
34.1
N.A.
N.A.
65.6
47.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
93.3
N.A.
0
N.A.
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
12
12
0
0
67
0
0
12
12
0
56
12
0
12
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
23
12
23
12
% D
% Glu:
0
0
0
0
0
12
0
0
12
12
0
0
56
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
56
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
12
12
0
56
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
12
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
23
0
0
12
12
0
0
0
0
0
12
0
% K
% Leu:
0
0
0
0
34
0
12
12
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
45
0
0
0
12
0
0
12
12
0
0
0
12
% N
% Pro:
0
12
0
0
45
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
12
0
0
0
0
56
0
0
0
0
0
0
% Q
% Arg:
0
12
0
45
0
12
56
0
12
0
56
0
0
0
0
% R
% Ser:
12
0
23
0
0
0
0
45
0
0
0
0
0
0
0
% S
% Thr:
0
56
0
0
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
56
0
0
12
0
0
0
0
0
56
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _