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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBB
All Species:
44.85
Human Site:
T55
Identified Species:
98.67
UniProt:
P07437
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07437
NP_821133.1
444
49671
T55
S
V
Y
Y
N
E
A
T
G
G
K
Y
V
P
R
Chimpanzee
Pan troglodytes
Q8WP14
444
49773
S55
N
V
Y
Y
N
E
A
S
G
G
R
Y
V
P
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERD7
450
50400
S55
S
V
Y
Y
N
E
A
S
S
H
K
Y
V
P
R
Rat
Rattus norvegicus
Q6P9T8
445
49782
T55
N
V
Y
Y
N
E
A
T
G
G
K
Y
V
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09244
444
49652
T55
S
V
Y
Y
N
E
A
T
G
G
K
Y
V
P
R
Frog
Xenopus laevis
Q91575
444
49709
T55
S
V
Y
Y
N
E
A
T
G
G
K
Y
V
P
R
Zebra Danio
Brachydanio rerio
NP_942113
444
49654
T55
S
V
Y
Y
N
E
A
T
G
G
K
Y
V
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24560
447
50129
S55
N
V
Y
Y
N
E
A
S
G
G
K
Y
V
P
R
Honey Bee
Apis mellifera
XP_392313
447
50157
S55
N
V
Y
Y
N
E
A
S
G
G
K
Y
V
P
R
Nematode Worm
Caenorhab. elegans
P41937
444
49782
S55
N
V
Y
Y
N
E
A
S
G
G
K
Y
V
P
R
Sea Urchin
Strong. purpuratus
XP_791790
447
50098
T55
N
V
Y
Y
N
E
A
T
G
G
K
Y
V
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
N.A.
N.A.
N.A.
91.3
97.3
N.A.
N.A.
100
99.7
98.6
N.A.
94.4
94.6
93
96.2
Protein Similarity:
100
95.2
N.A.
N.A.
N.A.
95.1
98.8
N.A.
N.A.
100
99.7
99.5
N.A.
97.7
98.2
97.5
98.4
P-Site Identity:
100
80
N.A.
N.A.
N.A.
80
93.3
N.A.
N.A.
100
100
100
N.A.
86.6
86.6
86.6
93.3
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
86.6
100
N.A.
N.A.
100
100
100
N.A.
100
100
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
91
91
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
91
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
55
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
100
% R
% Ser:
46
0
0
0
0
0
0
46
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% T
% Val:
0
100
0
0
0
0
0
0
0
0
0
0
100
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
100
100
0
0
0
0
0
0
0
100
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _