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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA3
All Species:
29.09
Human Site:
S227
Identified Species:
71.11
UniProt:
P07451
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07451
NP_005172.1
260
29557
S227
D
Q
M
A
K
L
R
S
L
L
S
S
A
E
N
Chimpanzee
Pan troglodytes
Q7M317
261
28893
S229
E
Q
L
A
Q
F
R
S
L
L
S
N
V
E
G
Rhesus Macaque
Macaca mulatta
P00916
261
28918
S229
E
Q
L
A
Q
F
R
S
L
L
S
N
V
E
G
Dog
Lupus familis
XP_544159
279
31304
T246
Q
Q
L
A
T
F
R
T
L
L
C
T
A
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P16015
260
29348
S227
D
Q
M
A
K
L
R
S
L
F
S
S
A
E
N
Rat
Rattus norvegicus
P14141
260
29413
S227
D
Q
M
A
K
L
R
S
L
F
A
S
A
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506835
260
29388
S227
D
Q
M
A
K
L
R
S
L
F
F
S
A
E
N
Chicken
Gallus gallus
P07630
260
28989
G227
E
Q
M
C
K
L
R
G
L
C
F
S
A
E
N
Frog
Xenopus laevis
NP_001080080
260
28985
S227
Q
Q
L
T
Q
L
R
S
L
F
F
N
A
E
G
Zebra Danio
Brachydanio rerio
Q92051
260
28659
S227
A
Q
M
A
K
F
R
S
L
L
F
S
S
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.4
54.7
52.3
N.A.
91.9
91.5
N.A.
86.1
62.3
54.6
55.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
70.8
72
67.3
N.A.
94.2
94.2
N.A.
92.3
75.7
69.6
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
53.3
46.6
N.A.
93.3
86.6
N.A.
86.6
66.6
46.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
80
66.6
N.A.
93.3
93.3
N.A.
86.6
73.3
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
80
0
0
0
0
0
0
10
0
70
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% C
% Asp:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
30
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% E
% Phe:
0
0
0
0
0
40
0
0
0
40
40
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
40
0
0
60
0
0
100
50
0
0
0
0
0
% L
% Met:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
30
0
0
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
20
100
0
0
30
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
80
0
0
40
60
10
0
0
% S
% Thr:
0
0
0
10
10
0
0
10
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _