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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CA3 All Species: 23.33
Human Site: T73 Identified Species: 57.04
UniProt: P07451 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07451 NP_005172.1 260 29557 T73 C R V V F D D T Y D R S M L R
Chimpanzee Pan troglodytes Q7M317 261 28893 N74 F H V N F E D N D N R S V L K
Rhesus Macaque Macaca mulatta P00916 261 28918 N74 F H V N F E D N D N R S V L K
Dog Lupus familis XP_544159 279 31304 T91 F S V D F D D T E D K S V L R
Cat Felis silvestris
Mouse Mus musculus P16015 260 29348 T73 C R V V F D D T Y D R S M L R
Rat Rattus norvegicus P14141 260 29413 T73 C R V V F D D T F D R S M L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506835 260 29388 T73 C R V V F D D T Y D R S M L R
Chicken Gallus gallus P07630 260 28989 S73 F N V E F D D S S D K S V L Q
Frog Xenopus laevis NP_001080080 260 28985 S73 F N V E F D D S E N K S V L T
Zebra Danio Brachydanio rerio Q92051 260 28659 D73 F Q V D F V D D D N S S T L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.4 54.7 52.3 N.A. 91.9 91.5 N.A. 86.1 62.3 54.6 55.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.8 72 67.3 N.A. 94.2 94.2 N.A. 92.3 75.7 69.6 68.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 40 60 N.A. 100 93.3 N.A. 100 46.6 40 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 66.6 73.3 N.A. 100 100 N.A. 100 73.3 66.6 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 20 0 70 100 10 30 60 0 0 0 0 0 % D
% Glu: 0 0 0 20 0 20 0 0 20 0 0 0 0 0 0 % E
% Phe: 60 0 0 0 100 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 30 0 0 0 20 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % M
% Asn: 0 20 0 20 0 0 0 20 0 40 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 40 0 0 0 0 0 0 0 0 60 0 0 0 50 % R
% Ser: 0 10 0 0 0 0 0 20 10 0 10 100 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 50 0 0 0 0 10 0 10 % T
% Val: 0 0 100 40 0 10 0 0 0 0 0 0 50 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _