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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRSS1 All Species: 33.33
Human Site: Y65 Identified Species: 91.67
UniProt: P07477 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07477 NP_002760.1 247 26558 Y65 V V S A G H C Y K S R I Q V R
Chimpanzee Pan troglodytes XP_001155576 299 31662 Y116 V V S A A H C Y K T R I Q V R
Rhesus Macaque Macaca mulatta NP_001040586 247 26314 Y65 V V S A G H C Y K T R I Q V R
Dog Lupus familis XP_532744 246 26259 Y65 V V S A A H C Y K S R I Q V R
Cat Felis silvestris
Mouse Mus musculus P07146 246 26185 Y65 V V S A A H C Y K Y R I Q V R
Rat Rattus norvegicus P00763 246 26209 Y65 V V S A A H C Y K S R I Q V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518130 246 26574 Y65 V V S A A H C Y M S R I Q V R
Chicken Gallus gallus Q90627 248 26051 Y67 V L S A A H C Y K S S I Q V K
Frog Xenopus laevis P70059 244 26061 Y63 V V S A A H C Y K S R I Q V R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.5 89.8 72.4 N.A. 74 78.1 N.A. 68.4 66.1 68.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72.5 94.3 82.5 N.A. 85.4 86.2 N.A. 82.1 81 83.4 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 93.3 93.3 N.A. 86.6 93.3 N.A. 86.6 73.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 93.3 N.A. 86.6 93.3 N.A. 86.6 86.6 93.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 100 78 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 89 0 0 0 0 0 12 % K
% Leu: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 89 0 0 0 89 % R
% Ser: 0 0 100 0 0 0 0 0 0 67 12 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 23 0 0 0 0 0 % T
% Val: 100 89 0 0 0 0 0 0 0 0 0 0 0 100 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _