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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRSS2 All Species: 16.06
Human Site: S150 Identified Species: 44.17
UniProt: P07478 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07478 NP_002761.1 247 26488 S150 G W G N T L S S G A D Y P D E
Chimpanzee Pan troglodytes XP_001155576 299 31662 V202 X X P X L L L V V T D Y P D E
Rhesus Macaque Macaca mulatta NP_001040585 247 26477 S150 G W G N T L S S G A D Y P D E
Dog Lupus familis XP_532744 246 26259 I150 G W G N T Q S I G Q N Y P D V
Cat Felis silvestris
Mouse Mus musculus P07146 246 26185 N150 G W G N T L S N G V N N P D L
Rat Rattus norvegicus P00763 246 26209 S150 G W G N T L S S G V N E P D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518130 246 26574 S150 G W G N T Q S S G S N Y P D L
Chicken Gallus gallus Q90629 248 26604 N152 G W G N T L S N G Y N Y P E L
Frog Xenopus laevis P70059 244 26061 S148 G W G N T L S S G T N Y P D L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.2 91 72.8 N.A. 76.5 77.7 N.A. 70.4 69.3 68.8 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72.9 95.5 83.4 N.A. 87.4 87.4 N.A. 83 81.8 83.8 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 100 66.6 N.A. 66.6 73.3 N.A. 73.3 66.6 80 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 100 73.3 N.A. 80 80 N.A. 86.6 86.6 86.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 23 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 34 0 0 89 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 12 0 12 34 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 89 0 89 0 0 0 0 0 89 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 12 78 12 0 0 0 0 0 0 0 56 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 89 0 0 0 23 0 0 67 12 0 0 0 % N
% Pro: 0 0 12 0 0 0 0 0 0 0 0 0 100 0 0 % P
% Gln: 0 0 0 0 0 23 0 0 0 12 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 89 56 0 12 0 0 0 0 0 % S
% Thr: 0 0 0 0 89 0 0 0 0 23 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 12 12 23 0 0 0 0 12 % V
% Trp: 0 89 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 12 0 78 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _