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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS2
All Species:
20.3
Human Site:
Y218
Identified Species:
55.83
UniProt:
P07478
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07478
NP_002761.1
247
26488
Y218
Q
G
I
V
S
W
G
Y
G
C
A
Q
K
N
R
Chimpanzee
Pan troglodytes
XP_001155576
299
31662
H270
Q
G
V
V
S
W
G
H
G
C
A
W
K
N
R
Rhesus Macaque
Macaca mulatta
NP_001040585
247
26477
Y218
Q
G
I
V
S
W
G
Y
G
C
A
Q
K
N
R
Dog
Lupus familis
XP_532744
246
26259
A218
Q
G
V
V
S
W
G
A
G
C
A
Q
K
G
K
Cat
Felis silvestris
Mouse
Mus musculus
P07146
246
26185
Y218
Q
G
I
V
S
W
G
Y
G
C
A
Q
P
D
A
Rat
Rattus norvegicus
P00763
246
26209
Y218
Q
G
I
V
S
W
G
Y
G
C
A
L
P
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518130
246
26574
Y218
Q
G
I
V
S
W
G
Y
G
C
A
M
K
G
K
Chicken
Gallus gallus
Q90629
248
26604
I220
Q
G
I
V
S
W
G
I
G
C
A
L
K
G
Y
Frog
Xenopus laevis
P70059
244
26061
Y216
Q
G
V
V
S
W
G
Y
G
C
A
Q
R
N
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
91
72.8
N.A.
76.5
77.7
N.A.
70.4
69.3
68.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.9
95.5
83.4
N.A.
87.4
87.4
N.A.
83
81.8
83.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
80
100
73.3
N.A.
80
73.3
N.A.
80
73.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
86.6
N.A.
86.6
80
N.A.
86.6
73.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
100
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
0
0
0
0
100
0
100
0
0
0
0
34
0
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
67
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
23
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
45
12
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% P
% Gln:
100
0
0
0
0
0
0
0
0
0
0
56
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
34
% R
% Ser:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
34
100
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
100
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
23
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _