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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHRNG All Species: 29.09
Human Site: S338 Identified Species: 64
UniProt: P07510 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07510 NP_005190.4 517 57883 S338 L R S P H T H S M A R G V R K
Chimpanzee Pan troglodytes Q5IS76 494 56903 T336 Y R T P T T H T M P R W V K T
Rhesus Macaque Macaca mulatta XP_001114133 524 57971 S346 L R S P H T H S M A Q G V R K
Dog Lupus familis XP_543289 519 58219 S338 L R S P H T H S M A H G V R K
Cat Felis silvestris
Mouse Mus musculus P04760 519 58727 S338 L R S P H T H S M A R G V R K
Rat Rattus norvegicus P18916 519 58603 S338 L R S P H T H S M A R G V R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520150 411 46360 G281 P E R A E V S G D E A A L W M
Chicken Gallus gallus P02713 514 58907 S339 L R T P N T H S M S Q R V R Q
Frog Xenopus laevis P05376 510 58059 S332 L R T P N T H S M S S T V R E
Zebra Danio Brachydanio rerio NP_996947 518 60339 V341 F R T P S T H V M T E W T K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P04755 521 59883 R332 F R G P R T H R M P M Y I R S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.4 88.5 90.1 N.A. 90.1 89.7 N.A. 58.9 66.5 60.5 45.9 N.A. 33.4 N.A. N.A. N.A.
Protein Similarity: 100 52.2 90.4 94.8 N.A. 94.2 94 N.A. 65.3 80.2 76.7 64 N.A. 53.1 N.A. N.A. N.A.
P-Site Identity: 100 46.6 93.3 93.3 N.A. 100 100 N.A. 0 60 60 33.3 N.A. 40 N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 93.3 N.A. 100 100 N.A. 6.6 93.3 86.6 53.3 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 46 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 10 0 0 0 0 10 10 0 0 0 19 % E
% Phe: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 10 0 0 0 46 0 0 0 % G
% His: 0 0 0 0 46 0 91 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 46 % K
% Leu: 64 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 91 0 10 0 0 0 10 % M
% Asn: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 91 0 0 0 0 0 19 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 10 % Q
% Arg: 0 91 10 0 10 0 0 10 0 0 37 10 0 73 0 % R
% Ser: 0 0 46 0 10 0 10 64 0 19 10 0 0 0 10 % S
% Thr: 0 0 37 0 10 91 0 10 0 10 0 10 10 0 10 % T
% Val: 0 0 0 0 0 10 0 10 0 0 0 0 73 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 19 0 10 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _