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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNG
All Species:
13.64
Human Site:
S378
Identified Species:
30
UniProt:
P07510
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07510
NP_005190.4
517
57883
S378
Q
S
R
L
Q
N
G
S
S
G
W
S
I
T
T
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
A384
R
P
A
K
G
K
L
A
S
H
G
E
P
R
H
Rhesus Macaque
Macaca mulatta
XP_001114133
524
57971
S386
Q
P
R
L
Q
N
G
S
S
G
W
S
I
T
T
Dog
Lupus familis
XP_543289
519
58219
S379
R
Q
L
Q
N
G
S
S
L
G
W
P
I
T
A
Cat
Felis silvestris
Mouse
Mus musculus
P04760
519
58727
S379
F
R
L
Q
N
G
S
S
S
G
W
P
I
M
A
Rat
Rattus norvegicus
P18916
519
58603
S379
L
R
L
Q
N
G
S
S
S
G
W
P
I
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520150
411
46360
L304
R
R
K
E
R
D
G
L
V
K
A
A
L
E
R
Chicken
Gallus gallus
P02713
514
58907
S375
P
Q
A
T
R
R
R
S
S
L
G
L
M
V
K
Frog
Xenopus laevis
P05376
510
58059
S370
A
P
L
M
R
R
S
S
S
L
G
L
M
M
K
Zebra Danio
Brachydanio rerio
NP_996947
518
60339
S379
S
A
L
P
R
R
S
S
S
L
G
Y
I
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04755
521
59883
G392
P
K
H
I
S
A
I
G
G
K
Q
S
K
M
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.4
88.5
90.1
N.A.
90.1
89.7
N.A.
58.9
66.5
60.5
45.9
N.A.
33.4
N.A.
N.A.
N.A.
Protein Similarity:
100
52.2
90.4
94.8
N.A.
94.2
94
N.A.
65.3
80.2
76.7
64
N.A.
53.1
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
33.3
N.A.
33.3
40
N.A.
6.6
13.3
13.3
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
40
N.A.
33.3
40
N.A.
46.6
26.6
33.3
33.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
19
0
0
10
0
10
0
0
10
10
0
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
10
0
10
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
28
28
10
10
46
37
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
10
0
0
0
0
0
55
0
0
% I
% Lys:
0
10
10
10
0
10
0
0
0
19
0
0
10
0
19
% K
% Leu:
10
0
46
19
0
0
10
10
10
28
0
19
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
19
37
0
% M
% Asn:
0
0
0
0
28
19
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
28
0
10
0
0
0
0
0
0
0
28
10
0
0
% P
% Gln:
19
19
0
28
19
0
0
0
0
0
10
0
0
0
10
% Q
% Arg:
28
28
19
0
37
28
10
0
0
0
0
0
0
10
10
% R
% Ser:
10
10
0
0
10
0
46
73
73
0
0
28
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
28
28
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
46
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _