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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFN1
All Species:
12.5
Human Site:
Y140
Identified Species:
27.5
UniProt:
P07737
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07737
NP_005013.1
140
15054
Y140
S
H
L
R
R
S
Q
Y
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001164143
104
11372
Rhesus Macaque
Macaca mulatta
XP_001102817
303
32122
F303
K
Y
L
R
D
S
G
F
_
_
_
_
_
_
_
Dog
Lupus familis
XP_849132
168
17690
Y168
S
H
L
R
R
S
Q
Y
_
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJV2
140
15014
F140
K
Y
L
R
D
S
G
F
_
_
_
_
_
_
_
Rat
Rattus norvegicus
P62963
140
14939
Y140
S
H
L
R
R
S
Q
Y
_
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507138
140
15036
F140
K
Y
L
R
D
S
G
F
_
_
_
_
_
_
_
Chicken
Gallus gallus
NP_001073228
140
15028
F140
K
Y
L
R
D
S
G
F
_
_
_
_
_
_
_
Frog
Xenopus laevis
NP_001080782
140
15141
F140
K
Y
L
R
D
M
G
F
_
_
_
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_958493
140
15215
Y140
E
Y
L
R
R
S
G
Y
_
_
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O22655
131
14083
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.4
26.3
60.7
N.A.
61.4
95.7
N.A.
60
61.4
59.2
60.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.1
35.3
64.8
N.A.
75.7
98.5
N.A.
73.5
75.7
73.5
76.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
37.5
100
N.A.
37.5
100
N.A.
37.5
37.5
25
62.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
62.5
100
N.A.
62.5
100
N.A.
62.5
62.5
50
75
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
25.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
46
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
46
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
55
0
0
0
0
0
0
0
0
% G
% His:
0
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
82
37
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
28
0
0
0
0
73
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
55
0
0
0
0
0
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
82
82
82
82
82
82
82
% _