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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BPGM All Species: 24.24
Human Site: Y142 Identified Species: 59.26
UniProt: P07738 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07738 NP_001715.1 259 30005 Y142 E I Y N D R R Y K V C D V P L
Chimpanzee Pan troglodytes Q8MKE8 254 28790 R140 Y S N I S K D R R Y A D L T E
Rhesus Macaque Macaca mulatta XP_001102609 236 27622 Y142 E I Y N D R R Y K V C D V P L
Dog Lupus familis XP_539820 260 30027 Y142 E I Y N D R R Y K V C D I P V
Cat Felis silvestris
Mouse Mus musculus P15327 259 29960 Y142 E I Y S D R R Y K V C D V P L
Rat Rattus norvegicus P16290 253 28737 R140 Y A S I S K D R R Y A G L K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512367 259 29777 Y142 E I Y N D R R Y K C C D V S P
Chicken Gallus gallus Q5ZLN1 254 28880 R140 F S T I S K D R R Y A D L T E
Frog Xenopus laevis NP_001085676 259 29895 Y142 E I H T D R R Y T T C D I P K
Zebra Danio Brachydanio rerio NP_001002630 259 29652 Y142 E I Y N D R R Y S T C D V P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.3 87.6 93.8 N.A. 92.2 50.9 N.A. 88.4 52.5 76.4 73.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 68.7 89.5 97.6 N.A. 98.4 70.6 N.A. 96.5 72.1 89.1 84.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 86.6 N.A. 93.3 0 N.A. 80 6.6 60 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 20 N.A. 80 26.6 73.3 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 30 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 70 0 0 0 0 % C
% Asp: 0 0 0 0 70 0 30 0 0 0 0 90 0 0 0 % D
% Glu: 70 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 70 0 30 0 0 0 0 0 0 0 0 20 0 0 % I
% Lys: 0 0 0 0 0 30 0 0 50 0 0 0 0 10 20 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 30 0 30 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 50 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 60 20 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 70 70 30 30 0 0 0 0 0 0 % R
% Ser: 0 20 10 10 30 0 0 0 10 0 0 0 0 10 0 % S
% Thr: 0 0 10 10 0 0 0 0 10 20 0 0 0 20 0 % T
% Val: 0 0 0 0 0 0 0 0 0 40 0 0 50 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 20 0 60 0 0 0 0 70 0 30 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _