Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD3E All Species: 4.55
Human Site: S77 Identified Species: 12.5
UniProt: P07766 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07766 NP_000724.1 207 23147 S77 E D D K N I G S D E D H L S L
Chimpanzee Pan troglodytes XP_001160698 207 23131 S77 E D D K N I G S D E D H L S L
Rhesus Macaque Macaca mulatta XP_001097204 198 22168 D71 K N K E D S G D R L F L P E F
Dog Lupus familis XP_536556 171 19274 P53 G T M G I Q L P H S R T L D L
Cat Felis silvestris
Mouse Mus musculus P22646 189 21375 L69 K H D K H L V L Q D F S E V E
Rat Rattus norvegicus P19377 173 19338 N55 V E R W L T K N K S L I L G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q98910 175 19043 V57 W K P D P K M V V N N K Y I I
Frog Xenopus laevis NP_001079051 167 18878 W48 E K G E S F L W T H D T K N I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres NP_001033071 172 19479 K54 G K W F K D K K E V S E G P A
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 84 20.2 N.A. 60.8 20.2 N.A. N.A. 42.5 24.1 N.A. 26 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 88.8 40.5 N.A. 72.9 39.1 N.A. N.A. 57 43 N.A. 43.9 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 13.3 N.A. 13.3 6.6 N.A. N.A. 0 13.3 N.A. 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 13.3 N.A. 40 20 N.A. N.A. 13.3 40 N.A. 6.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 23 34 12 12 12 0 12 23 12 34 0 0 12 0 % D
% Glu: 34 12 0 23 0 0 0 0 12 23 0 12 12 12 12 % E
% Phe: 0 0 0 12 0 12 0 0 0 0 23 0 0 0 12 % F
% Gly: 23 0 12 12 0 0 34 0 0 0 0 0 12 12 0 % G
% His: 0 12 0 0 12 0 0 0 12 12 0 23 0 0 0 % H
% Ile: 0 0 0 0 12 23 0 0 0 0 0 12 0 12 23 % I
% Lys: 23 34 12 34 12 12 23 12 12 0 0 12 12 0 12 % K
% Leu: 0 0 0 0 12 12 23 12 0 12 12 12 45 0 34 % L
% Met: 0 0 12 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 0 23 0 0 12 0 12 12 0 0 12 0 % N
% Pro: 0 0 12 0 12 0 0 12 0 0 0 0 12 12 0 % P
% Gln: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 0 0 12 0 12 0 0 0 0 % R
% Ser: 0 0 0 0 12 12 0 23 0 23 12 12 0 23 0 % S
% Thr: 0 12 0 0 0 12 0 0 12 0 0 23 0 0 0 % T
% Val: 12 0 0 0 0 0 12 12 12 12 0 0 0 12 0 % V
% Trp: 12 0 12 12 0 0 0 12 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _