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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD3E
All Species:
4.55
Human Site:
Y149
Identified Species:
12.5
UniProt:
P07766
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07766
NP_000724.1
207
23147
Y149
G
G
L
L
L
L
V
Y
Y
W
S
K
N
R
K
Chimpanzee
Pan troglodytes
XP_001160698
207
23131
Y149
G
G
L
L
L
L
V
Y
Y
W
S
K
N
R
K
Rhesus Macaque
Macaca mulatta
XP_001097204
198
22168
W142
L
L
L
L
V
Y
Y
W
S
K
N
R
K
A
K
Dog
Lupus familis
XP_536556
171
19274
C124
L
L
A
L
G
V
Y
C
F
A
G
H
E
T
G
Cat
Felis silvestris
Mouse
Mus musculus
P22646
189
21375
K140
W
S
K
N
R
K
A
K
A
K
P
V
T
R
G
Rat
Rattus norvegicus
P19377
173
19338
A126
A
L
G
V
Y
C
F
A
G
H
E
T
G
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q98910
175
19043
K128
V
Y
Y
F
S
K
N
K
K
G
Q
S
R
A
A
Frog
Xenopus laevis
NP_001079051
167
18878
I120
D
I
I
M
I
G
L
I
A
I
A
V
Y
C
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001033071
172
19479
K125
V
M
V
Y
K
C
A
K
K
R
S
S
A
A
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
84
20.2
N.A.
60.8
20.2
N.A.
N.A.
42.5
24.1
N.A.
26
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
88.8
40.5
N.A.
72.9
39.1
N.A.
N.A.
57
43
N.A.
43.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
6.6
N.A.
6.6
6.6
N.A.
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
20
N.A.
6.6
13.3
N.A.
N.A.
0
33.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
0
23
12
23
12
12
0
12
34
12
% A
% Cys:
0
0
0
0
0
23
0
12
0
0
0
0
0
12
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% E
% Phe:
0
0
0
12
0
0
12
0
12
0
0
0
0
0
0
% F
% Gly:
23
23
12
0
12
12
0
0
12
12
12
0
12
0
23
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% H
% Ile:
0
12
12
0
12
0
0
12
0
12
0
0
0
0
0
% I
% Lys:
0
0
12
0
12
23
0
34
23
23
0
23
12
0
34
% K
% Leu:
23
34
34
45
23
23
12
0
0
0
0
0
0
0
23
% L
% Met:
0
12
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
12
0
0
0
12
0
23
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
12
0
12
12
45
0
% R
% Ser:
0
12
0
0
12
0
0
0
12
0
34
23
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
12
12
12
0
% T
% Val:
23
0
12
12
12
12
23
0
0
0
0
23
0
0
12
% V
% Trp:
12
0
0
0
0
0
0
12
0
23
0
0
0
0
0
% W
% Tyr:
0
12
12
12
12
12
23
23
23
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _