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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPRS
All Species:
8.48
Human Site:
S1336
Identified Species:
16.97
UniProt:
P07814
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07814
NP_004437.2
1512
170591
S1336
D
Y
R
R
R
L
L
S
V
N
I
R
V
R
A
Chimpanzee
Pan troglodytes
XP_001172425
1512
170609
R1336
D
Y
R
R
R
L
L
R
V
N
I
R
V
R
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849468
1509
169841
S1333
D
Y
R
R
R
L
L
S
V
N
V
R
V
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGC7
1512
170035
G1336
E
Y
R
R
R
L
L
G
A
N
I
R
V
R
V
Rat
Rattus norvegicus
NP_001019409
1486
166763
G1310
E
Y
R
R
R
L
L
G
A
D
I
R
A
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511623
1260
140891
I1113
W
E
L
K
G
V
P
I
R
L
E
V
G
P
R
Chicken
Gallus gallus
NP_001006398
1601
179906
S1425
E
Y
R
K
R
L
L
S
A
N
V
R
V
R
A
Frog
Xenopus laevis
NP_001121346
1499
169430
N1323
Q
Y
L
K
R
L
L
N
V
D
V
R
A
R
A
Zebra Danio
Brachydanio rerio
XP_690524
1511
168753
K1335
K
Y
L
S
R
L
Q
K
A
D
I
R
V
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P28668
1714
189393
G1536
A
L
E
K
R
L
V
G
G
G
V
R
C
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786677
1621
178355
A1457
N
Y
V
K
I
L
K
A
G
G
I
R
A
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38708
688
77368
L541
G
I
P
I
R
I
E
L
G
P
K
D
I
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
93.1
N.A.
89.3
85.2
N.A.
54.4
78.7
76.1
73.8
N.A.
51.6
N.A.
N.A.
55
Protein Similarity:
100
99.8
N.A.
96.3
N.A.
94.9
91.4
N.A.
65.4
86.5
86.7
85.2
N.A.
65.4
N.A.
N.A.
69
P-Site Identity:
100
93.3
N.A.
80
N.A.
73.3
60
N.A.
0
73.3
53.3
46.6
N.A.
20
N.A.
N.A.
26.6
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
80
73.3
N.A.
13.3
93.3
80
60
N.A.
40
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
34
0
0
0
25
0
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
25
0
0
0
0
0
0
0
0
25
0
9
0
0
0
% D
% Glu:
25
9
9
0
0
0
9
0
0
0
9
0
0
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
0
0
25
25
17
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
9
9
0
9
0
0
50
0
9
0
0
% I
% Lys:
9
0
0
42
0
0
9
9
0
0
9
0
0
17
9
% K
% Leu:
0
9
25
0
0
84
59
9
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
9
0
42
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
9
0
0
9
0
0
0
9
0
% P
% Gln:
9
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
50
42
84
0
0
9
9
0
0
84
0
50
9
% R
% Ser:
0
0
0
9
0
0
0
25
0
0
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
9
9
0
34
0
34
9
50
0
25
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _