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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPRS All Species: 34.55
Human Site: Y1269 Identified Species: 69.09
UniProt: P07814 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07814 NP_004437.2 1512 170591 Y1269 P G E K Q F A Y Q N S W G L T
Chimpanzee Pan troglodytes XP_001172425 1512 170609 Y1269 P G E K Q F A Y Q N S W G L T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849468 1509 169841 Y1266 P G E K Q F A Y Q N S W G L T
Cat Felis silvestris
Mouse Mus musculus Q8CGC7 1512 170035 Y1269 P G E K Q F A Y Q C S W G L T
Rat Rattus norvegicus NP_001019409 1486 166763 Y1243 P G E K Q F A Y Q C S W G L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511623 1260 140891 I1059 V V V I P C G I T N S L S E E
Chicken Gallus gallus NP_001006398 1601 179906 Y1358 P G E K Q Y A Y Q N S W G I T
Frog Xenopus laevis NP_001121346 1499 169430 Y1256 P G L K Q Y A Y Q N S W G L S
Zebra Danio Brachydanio rerio XP_690524 1511 168753 Y1268 P G E K Q L A Y Q N S W G I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P28668 1714 189393 Y1469 T Q Q K K Y V Y Q N S W G I T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786677 1621 178355 F1390 P N A H K Y V F Q N S W G I T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38708 688 77368 T487 P V G I T K K T S E E Q R K H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 93.1 N.A. 89.3 85.2 N.A. 54.4 78.7 76.1 73.8 N.A. 51.6 N.A. N.A. 55
Protein Similarity: 100 99.8 N.A. 96.3 N.A. 94.9 91.4 N.A. 65.4 86.5 86.7 85.2 N.A. 65.4 N.A. N.A. 69
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 13.3 86.6 80 86.6 N.A. 53.3 N.A. N.A. 46.6
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 13.3 100 93.3 93.3 N.A. 80 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 67 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 17 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 59 0 0 0 0 0 0 9 9 0 0 9 9 % E
% Phe: 0 0 0 0 0 42 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 67 9 0 0 0 9 0 0 0 0 0 84 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 17 0 0 0 9 0 0 0 0 0 34 0 % I
% Lys: 0 0 0 75 17 9 9 0 0 0 0 0 0 9 0 % K
% Leu: 0 0 9 0 0 9 0 0 0 0 0 9 0 50 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 75 0 0 0 0 0 % N
% Pro: 84 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 9 0 67 0 0 0 84 0 0 9 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 9 0 92 0 9 0 9 % S
% Thr: 9 0 0 0 9 0 0 9 9 0 0 0 0 0 75 % T
% Val: 9 17 9 0 0 0 17 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 84 0 0 0 % W
% Tyr: 0 0 0 0 0 34 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _