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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LDHC
All Species:
31.82
Human Site:
Y172
Identified Species:
77.78
UniProt:
P07864
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07864
NP_002292.1
332
36311
Y172
L
D
S
A
R
F
R
Y
L
I
G
E
K
L
G
Chimpanzee
Pan troglodytes
Q5R1W9
332
36644
Y172
L
D
S
A
R
F
R
Y
L
M
G
E
R
L
G
Rhesus Macaque
Macaca mulatta
XP_001082436
394
43206
Y234
L
D
S
A
R
F
R
Y
L
I
G
E
K
L
G
Dog
Lupus familis
XP_534085
420
45422
Y260
L
D
S
A
R
F
R
Y
L
I
G
E
K
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P06151
332
36480
Y172
L
D
S
A
R
F
R
Y
L
M
G
E
R
L
G
Rat
Rattus norvegicus
P04642
332
36432
Y172
L
D
S
A
R
F
R
Y
L
M
G
E
R
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
NP_001121092
332
36433
Y172
L
D
S
A
R
F
R
Y
L
M
G
E
R
L
G
Chicken
Gallus gallus
P00340
332
36496
H172
L
D
S
A
R
F
R
H
L
M
G
E
R
L
G
Frog
Xenopus laevis
P42120
334
36474
H173
L
D
S
A
R
F
R
H
L
I
A
E
K
L
G
Zebra Danio
Brachydanio rerio
Q9PVK5
333
36228
Y173
L
D
S
A
R
F
R
Y
L
M
G
E
K
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.3
81.9
70
N.A.
74.6
74.6
N.A.
77.1
71.9
68.5
68.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.8
83.2
76.9
N.A.
87.6
88.5
N.A.
88.5
86.1
80.5
82.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
86.6
86.6
N.A.
86.6
80
86.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
100
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% E
% Phe:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
90
0
0
0
100
% G
% His:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% K
% Leu:
100
0
0
0
0
0
0
0
100
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
100
0
100
0
0
0
0
0
50
0
0
% R
% Ser:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _