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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GALT All Species: 21.21
Human Site: Y221 Identified Species: 51.85
UniProt: P07902 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07902 NP_000146.2 379 43363 Y221 G E P L L M E Y S R Q E L L R
Chimpanzee Pan troglodytes XP_001163419 379 43266 Y221 G E P L L M E Y S R Q E L L R
Rhesus Macaque Macaca mulatta XP_001095205 379 43238 Y221 G E P L L M E Y S R Q E L L R
Dog Lupus familis XP_852579 380 43666 Y221 G E P L L M E Y G R Q E L L R
Cat Felis silvestris
Mouse Mus musculus Q03249 379 43214 Y221 G K P L L L E Y G H Q E L L R
Rat Rattus norvegicus P43424 379 43296 Y221 G K P L L L E Y G H Q E L L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMA2 350 40429 R194 A Y Y A T N E R P M L A D Y V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27536 352 41024 K196 K H F E K H G K V M L M D Y L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P08431 366 42367 H209 F D K Y K R E H N T D L F A D
Red Bread Mold Neurospora crassa Q7RYE7 392 44871 K229 K E L A Q M T K Y H R E H K G
Conservation
Percent
Protein Identity: 100 99.2 97.3 92.6 N.A. 91 88.9 N.A. N.A. N.A. N.A. N.A. N.A. 53.5 N.A. 46.9 N.A.
Protein Similarity: 100 99.4 98.9 95.5 N.A. 94.7 93.9 N.A. N.A. N.A. N.A. N.A. N.A. 67.5 N.A. 63.5 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 73.3 73.3 N.A. N.A. N.A. N.A. N.A. N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. N.A. N.A. N.A. N.A. N.A. 6.6 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 45.3 44.9
Protein Similarity: N.A. N.A. N.A. N.A. 62.8 58.9
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 20
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 20 0 0 0 0 0 0 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 10 0 20 0 10 % D
% Glu: 0 50 0 10 0 0 80 0 0 0 0 70 0 0 0 % E
% Phe: 10 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 60 0 0 0 0 0 10 0 30 0 0 0 0 0 10 % G
% His: 0 10 0 0 0 10 0 10 0 30 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 20 20 10 0 20 0 0 20 0 0 0 0 0 10 0 % K
% Leu: 0 0 10 60 60 20 0 0 0 0 20 10 60 60 10 % L
% Met: 0 0 0 0 0 50 0 0 0 20 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 60 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 60 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 10 0 40 10 0 0 0 60 % R
% Ser: 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 10 0 10 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 10 0 0 0 60 10 0 0 0 0 20 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _