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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRNPC All Species: 23.94
Human Site: S120 Identified Species: 65.83
UniProt: P07910 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07910 NP_001070910.1 306 33670 S120 S P S P L L S S S F D L D Y D
Chimpanzee Pan troglodytes XP_001152335 293 32198 S107 S A A E M Y G S S F D L D Y G
Rhesus Macaque Macaca mulatta XP_001096688 307 33803 S120 S P S P L L R S G N F I L D Y
Dog Lupus familis XP_851458 302 33240 S115 V P E H P S P S S F D L D Y D
Cat Felis silvestris
Mouse Mus musculus Q9Z204 313 34366 S120 S P S P L L S S S F D L D Y D
Rat Rattus norvegicus NP_001020804 298 32839 S107 S A A E M Y G S S F D L D Y D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511210 307 33796 S120 S P S P L L S S S F D L D Y D
Chicken Gallus gallus
Frog Xenopus laevis P19600 282 30931 S108 S A A D M Y G S S F D L E Y D
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24491 197 21114 A39 K L N S V W I A F N P P G F A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 98.6 96.7 N.A. 95.5 92.1 N.A. 97.7 N.A. 75.8 N.A. N.A. 21.2 N.A. N.A. N.A.
Protein Similarity: 100 89.8 99 97.3 N.A. 96.4 93.4 N.A. 98.6 N.A. 83 N.A. N.A. 31.3 N.A. N.A. N.A.
P-Site Identity: 100 53.3 46.6 60 N.A. 100 60 N.A. 100 N.A. 53.3 N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 66.6 53.3 60 N.A. 100 73.3 N.A. 100 N.A. 73.3 N.A. N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 34 0 0 0 0 12 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 0 0 0 0 0 0 78 0 67 12 67 % D
% Glu: 0 0 12 23 0 0 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 78 12 0 0 12 0 % F
% Gly: 0 0 0 0 0 0 34 0 12 0 0 0 12 0 12 % G
% His: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 0 0 12 0 0 0 % I
% Lys: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 12 0 0 45 45 0 0 0 0 0 78 12 0 0 % L
% Met: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 23 0 0 0 0 0 % N
% Pro: 0 56 0 45 12 0 12 0 0 0 12 12 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % R
% Ser: 78 0 45 12 0 12 34 89 78 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 12 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 34 0 0 0 0 0 0 0 78 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _