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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAMB1
All Species:
39.39
Human Site:
Y258
Identified Species:
66.67
UniProt:
P07942
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07942
NP_002282.2
1786
198066
Y258
R
M
E
I
R
E
K
Y
Y
Y
A
V
Y
D
M
Chimpanzee
Pan troglodytes
XP_001165635
1786
198155
Y258
R
M
E
I
R
E
K
Y
Y
Y
A
V
Y
D
M
Rhesus Macaque
Macaca mulatta
XP_001090393
1960
216360
Y432
R
M
E
I
R
E
K
Y
Y
Y
A
V
Y
D
M
Dog
Lupus familis
XP_533089
1655
182573
H236
G
V
C
D
D
C
Q
H
N
T
M
G
R
N
C
Cat
Felis silvestris
Mouse
Mus musculus
P02469
1786
196886
Y258
R
M
E
I
R
E
K
Y
Y
Y
A
V
Y
D
M
Rat
Rattus norvegicus
P15800
1801
196455
Y273
R
R
E
I
R
E
K
Y
Y
Y
A
L
Y
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506672
1850
202794
G252
L
Y
E
L
V
V
R
G
S
C
F
C
H
G
H
Chicken
Gallus gallus
XP_415943
2147
234237
Y618
R
M
E
I
R
E
K
Y
Y
Y
A
I
Y
D
M
Frog
Xenopus laevis
NP_001088164
1783
197665
Y258
R
V
E
I
K
E
K
Y
Y
Y
A
L
Y
E
L
Zebra Danio
Brachydanio rerio
Q8JHV6
1827
203534
Y254
K
R
N
P
Q
D
K
Y
Y
Y
A
L
Y
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11046
1788
198315
Y275
R
L
E
N
E
E
K
Y
Y
Y
G
I
S
N
M
Honey Bee
Apis mellifera
XP_001122457
1816
202931
Y308
R
A
E
I
R
E
K
Y
Y
Y
A
I
Q
N
M
Nematode Worm
Caenorhab. elegans
Q18823
1535
170219
Y116
T
M
Q
E
G
Q
Q
Y
P
T
T
T
N
L
T
Sea Urchin
Strong. purpuratus
XP_001195934
1658
183520
G239
G
D
H
L
F
D
D
G
D
E
V
F
N
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.1
85.3
N.A.
92.6
50.7
N.A.
42.2
66.5
55.3
39.9
N.A.
40.8
42
26.9
43.5
Protein Similarity:
100
99.7
90.7
89.5
N.A.
96.6
67.9
N.A.
59.1
74.3
72.6
57.5
N.A.
60
58.9
44.2
60.3
P-Site Identity:
100
100
100
0
N.A.
100
73.3
N.A.
6.6
93.3
66.6
46.6
N.A.
53.3
73.3
13.3
0
P-Site Similarity:
100
100
100
26.6
N.A.
100
93.3
N.A.
26.6
100
100
80
N.A.
73.3
86.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
65
0
0
0
0
% A
% Cys:
0
0
8
0
0
8
0
0
0
8
0
8
0
0
8
% C
% Asp:
0
8
0
8
8
15
8
0
8
0
0
0
0
36
0
% D
% Glu:
0
0
72
8
8
65
0
0
0
8
0
0
0
22
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
15
0
0
0
8
0
0
15
0
0
8
8
0
8
0
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
58
0
0
0
0
0
0
0
22
0
0
0
% I
% Lys:
8
0
0
0
8
0
72
0
0
0
0
0
0
8
0
% K
% Leu:
8
8
0
15
0
0
0
0
0
0
0
22
0
8
15
% L
% Met:
0
43
0
0
0
0
0
0
0
0
8
0
0
0
58
% M
% Asn:
0
0
8
8
0
0
0
0
8
0
0
0
15
22
0
% N
% Pro:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
8
15
0
0
0
0
0
8
0
0
% Q
% Arg:
65
15
0
0
50
0
8
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
15
8
8
0
0
8
% T
% Val:
0
15
0
0
8
8
0
0
0
0
8
29
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
79
72
72
0
0
58
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _