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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAMB1
All Species:
21.82
Human Site:
Y557
Identified Species:
36.92
UniProt:
P07942
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07942
NP_002282.2
1786
198066
Y557
A
T
L
D
H
Y
L
Y
E
A
E
E
A
N
L
Chimpanzee
Pan troglodytes
XP_001165635
1786
198155
Y557
A
T
L
D
H
Y
L
Y
E
A
E
E
A
N
L
Rhesus Macaque
Macaca mulatta
XP_001090393
1960
216360
Y731
A
T
L
D
H
Y
L
Y
E
A
E
E
A
N
L
Dog
Lupus familis
XP_533089
1655
182573
G504
V
L
I
V
Q
R
P
G
K
I
P
T
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P02469
1786
196886
Y557
T
T
L
D
H
Y
I
Y
E
A
E
E
A
N
L
Rat
Rattus norvegicus
P15800
1801
196455
T571
R
P
F
L
D
H
L
T
W
E
A
E
G
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506672
1850
202794
S572
R
Q
R
S
P
T
R
S
P
P
S
H
S
P
A
Chicken
Gallus gallus
XP_415943
2147
234237
Y917
I
S
L
D
H
Y
I
Y
E
A
E
E
A
N
L
Frog
Xenopus laevis
NP_001088164
1783
197665
Y557
I
H
L
D
H
Y
T
Y
E
A
E
S
A
V
H
Zebra Danio
Brachydanio rerio
Q8JHV6
1827
203534
V637
K
I
S
N
G
R
L
V
V
V
K
R
E
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11046
1788
198315
A577
L
L
P
E
V
H
E
A
E
V
V
D
E
C
I
Honey Bee
Apis mellifera
XP_001122457
1816
202931
E606
S
L
D
F
L
I
Y
E
G
E
L
S
R
A
T
Nematode Worm
Caenorhab. elegans
Q18823
1535
170219
Y384
W
R
R
P
G
E
N
Y
C
V
A
C
G
C
N
Sea Urchin
Strong. purpuratus
XP_001195934
1658
183520
C507
G
G
S
Y
N
N
S
C
N
Q
A
S
G
Q
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.1
85.3
N.A.
92.6
50.7
N.A.
42.2
66.5
55.3
39.9
N.A.
40.8
42
26.9
43.5
Protein Similarity:
100
99.7
90.7
89.5
N.A.
96.6
67.9
N.A.
59.1
74.3
72.6
57.5
N.A.
60
58.9
44.2
60.3
P-Site Identity:
100
100
100
0
N.A.
86.6
13.3
N.A.
0
80
60
6.6
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
20
N.A.
6.6
93.3
60
20
N.A.
33.3
6.6
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
0
0
0
8
0
43
22
0
43
15
8
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
8
0
15
8
% C
% Asp:
0
0
8
43
8
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
8
0
8
8
8
50
15
43
43
15
0
0
% E
% Phe:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
15
0
0
8
8
0
0
0
22
0
0
% G
% His:
0
8
0
0
43
15
0
0
0
0
0
8
0
0
15
% H
% Ile:
15
8
8
0
0
8
15
0
0
8
0
0
0
0
8
% I
% Lys:
8
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% K
% Leu:
8
22
43
8
8
0
36
0
0
0
8
0
0
0
36
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
8
8
0
8
0
0
0
0
36
8
% N
% Pro:
0
8
8
8
8
0
8
0
8
8
8
0
0
8
0
% P
% Gln:
0
8
0
0
8
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
15
8
15
0
0
15
8
0
0
0
0
8
8
0
15
% R
% Ser:
8
8
15
8
0
0
8
8
0
0
8
22
15
8
0
% S
% Thr:
8
29
0
0
0
8
8
8
0
0
0
8
0
0
8
% T
% Val:
8
0
0
8
8
0
0
8
8
22
8
0
0
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
43
8
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _