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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPM2 All Species: 30.33
Human Site: T282 Identified Species: 60.66
UniProt: P07951 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07951 NP_003280.2 284 32851 T282 D N A L N D I T S L _ _ _ _ _
Chimpanzee Pan troglodytes XP_001167009 322 36729 P282 A L T D T P S P C T E P T H K
Rhesus Macaque Macaca mulatta XP_001087314 264 30581 S261 D D L E G K R S L Y K _ _ _ _
Dog Lupus familis XP_866572 284 32782 N282 D Q T L L E L N N L _ _ _ _ _
Cat Felis silvestris
Mouse Mus musculus P21107 284 32844 T282 D H A L N D M T S I _ _ _ _ _
Rat Rattus norvegicus P58775 284 32818 T282 D N A L N D I T S L _ _ _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P19352 284 32758 T282 D N A L N D I T S L _ _ _ _ _
Frog Xenopus laevis Q01173 284 32632 T282 D H A L N D M T S I _ _ _ _ _
Zebra Danio Brachydanio rerio P13104 284 32704 T282 D H A L N D M T S I _ _ _ _ _
Tiger Blowfish Takifugu rubipres NP_001027746 284 32727 T282 D L A L N D M T S I _ _ _ _ _
Fruit Fly Dros. melanogaster P49455 518 54567 I282 D E A F V D L I K G L E P F W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22866 284 32985 S282 D S T F Q E L S G Y _ _ _ _ _
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.3 91.1 92.2 N.A. 85.2 99.6 N.A. N.A. 97.5 85.5 85.9 85.5 29.1 N.A. 54.5 N.A.
Protein Similarity: 100 84.1 92.2 95.4 N.A. 96.1 100 N.A. N.A. 99.3 96.4 95 94.7 42.2 N.A. 75.3 N.A.
P-Site Identity: 100 0 9 30 N.A. 70 100 N.A. N.A. 100 70 70 70 20 N.A. 10 N.A.
P-Site Similarity: 100 0 27.2 60 N.A. 100 100 N.A. N.A. 100 100 100 90 26.6 N.A. 50 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 92 9 0 9 0 67 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 9 0 17 0 0 0 0 9 9 0 0 0 % E
% Phe: 0 0 0 17 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 9 0 0 0 9 9 0 0 0 0 0 % G
% His: 0 25 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 25 9 0 34 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 9 0 0 9 0 9 0 0 0 9 % K
% Leu: 0 17 9 67 9 0 25 0 9 34 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % M
% Asn: 0 25 0 0 59 0 0 9 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 9 0 9 0 0 0 9 9 0 0 % P
% Gln: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 0 0 0 9 17 59 0 0 0 0 0 0 % S
% Thr: 0 0 25 0 9 0 0 59 0 9 0 0 9 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 75 84 84 84 84 % _