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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPM2 All Species: 45.45
Human Site: Y162 Identified Species: 90.91
UniProt: P07951 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07951 NP_003280.2 284 32851 Y162 A E D S D R K Y E E V A R K L
Chimpanzee Pan troglodytes XP_001167009 322 36729 Y162 A E D S D R K Y E E V A R K L
Rhesus Macaque Macaca mulatta XP_001087314 264 30581 L143 K D E E K M E L Q E M Q L K E
Dog Lupus familis XP_866572 284 32782 Y162 A E D S D R K Y E E V A R K L
Cat Felis silvestris
Mouse Mus musculus P21107 284 32844 Y162 A E E A D R K Y E E V A R K L
Rat Rattus norvegicus P58775 284 32818 Y162 A E D S D R K Y E E V A R K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P19352 284 32758 Y162 A E E A D R K Y E E V A R K L
Frog Xenopus laevis Q01173 284 32632 Y162 A E E A D R K Y E E V A R K L
Zebra Danio Brachydanio rerio P13104 284 32704 Y162 A E E A D R K Y E E V A R K L
Tiger Blowfish Takifugu rubipres NP_001027746 284 32727 Y162 A E D S D R K Y E E V A R K L
Fruit Fly Dros. melanogaster P49455 518 54567 Y162 A E E A D K K Y D E V A R K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22866 284 32985 Y162 A E E A D R K Y D E V A R K L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.3 91.1 92.2 N.A. 85.2 99.6 N.A. N.A. 97.5 85.5 85.9 85.5 29.1 N.A. 54.5 N.A.
Protein Similarity: 100 84.1 92.2 95.4 N.A. 96.1 100 N.A. N.A. 99.3 96.4 95 94.7 42.2 N.A. 75.3 N.A.
P-Site Identity: 100 100 13.3 100 N.A. 86.6 100 N.A. N.A. 86.6 86.6 86.6 100 73.3 N.A. 80 N.A.
P-Site Similarity: 100 100 46.6 100 N.A. 100 100 N.A. N.A. 100 100 100 100 100 N.A. 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 92 0 0 50 0 0 0 0 0 0 0 92 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 42 0 92 0 0 0 17 0 0 0 0 0 0 % D
% Glu: 0 92 59 9 0 0 9 0 75 100 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 9 9 92 0 0 0 0 0 0 100 0 % K
% Leu: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 92 % L
% Met: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % Q
% Arg: 0 0 0 0 0 84 0 0 0 0 0 0 92 0 0 % R
% Ser: 0 0 0 42 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 92 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 92 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _