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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPM2
All Species:
29.39
Human Site:
Y261
Identified Species:
58.79
UniProt:
P07951
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07951
NP_003280.2
284
32851
Y261
D
D
L
E
D
E
V
Y
A
Q
K
M
K
Y
K
Chimpanzee
Pan troglodytes
XP_001167009
322
36729
S261
D
D
L
E
E
S
T
S
I
A
T
T
E
H
W
Rhesus Macaque
Macaca mulatta
XP_001087314
264
30581
E240
K
E
A
E
T
R
A
E
F
A
E
R
S
V
A
Dog
Lupus familis
XP_866572
284
32782
A261
D
D
L
E
E
T
L
A
S
A
K
E
E
N
V
Cat
Felis silvestris
Mouse
Mus musculus
P21107
284
32844
Y261
D
D
L
E
D
E
L
Y
A
Q
K
L
K
Y
K
Rat
Rattus norvegicus
P58775
284
32818
Y261
D
D
L
E
D
E
V
Y
A
Q
K
M
K
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19352
284
32758
Y261
D
D
L
E
D
E
V
Y
A
Q
K
M
K
Y
K
Frog
Xenopus laevis
Q01173
284
32632
Y261
D
D
L
E
D
E
L
Y
A
Q
K
L
K
Y
K
Zebra Danio
Brachydanio rerio
P13104
284
32704
Y261
D
D
L
E
D
E
L
Y
A
Q
K
L
K
Y
K
Tiger Blowfish
Takifugu rubipres
NP_001027746
284
32727
Y261
D
D
L
E
D
E
L
Y
A
Q
K
L
K
Y
K
Fruit Fly
Dros. melanogaster
P49455
518
54567
I261
D
R
L
E
D
D
L
I
V
E
K
E
R
Y
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22866
284
32985
V261
D
R
L
E
D
E
L
V
H
E
K
E
R
Y
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.3
91.1
92.2
N.A.
85.2
99.6
N.A.
N.A.
97.5
85.5
85.9
85.5
29.1
N.A.
54.5
N.A.
Protein Similarity:
100
84.1
92.2
95.4
N.A.
96.1
100
N.A.
N.A.
99.3
96.4
95
94.7
42.2
N.A.
75.3
N.A.
P-Site Identity:
100
26.6
6.6
33.3
N.A.
86.6
100
N.A.
N.A.
100
86.6
86.6
86.6
40
N.A.
53.3
N.A.
P-Site Similarity:
100
46.6
20
60
N.A.
100
100
N.A.
N.A.
100
100
100
100
66.6
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
9
9
59
25
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
92
75
0
0
75
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
100
17
67
0
9
0
17
9
25
17
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
84
0
59
0
67
% K
% Leu:
0
0
92
0
0
0
59
0
0
0
0
34
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
59
0
0
0
0
0
% Q
% Arg:
0
17
0
0
0
9
0
0
0
0
0
9
17
0
0
% R
% Ser:
0
0
0
0
0
9
0
9
9
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
9
9
9
0
0
0
9
9
0
0
0
% T
% Val:
0
0
0
0
0
0
25
9
9
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
0
75
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _