KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFTPB
All Species:
9.39
Human Site:
T289
Identified Species:
25.83
UniProt:
P07988
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07988
NP_000533.2
381
42117
T289
S
A
G
P
R
S
P
T
G
E
W
L
P
R
D
Chimpanzee
Pan troglodytes
XP_001168379
377
41518
T285
S
A
G
P
R
S
P
T
G
E
W
L
P
R
D
Rhesus Macaque
Macaca mulatta
XP_001089841
381
42159
T289
S
T
G
P
G
S
P
T
G
E
W
L
P
Q
D
Dog
Lupus familis
XP_861531
513
56732
D394
V
R
V
I
K
P
K
D
G
G
F
C
E
V
C
Cat
Felis silvestris
Mouse
Mus musculus
P50405
377
41710
I285
L
P
A
V
E
P
L
I
E
E
W
P
L
Q
D
Rat
Rattus norvegicus
P22355
376
41571
I284
L
P
A
L
E
P
L
I
E
K
W
P
L
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518767
357
39232
P250
P
P
P
A
L
W
L
P
S
A
P
D
C
G
L
Chicken
Gallus gallus
O13035
518
57583
T307
K
A
T
V
Q
E
K
T
F
S
V
C
E
I
C
Frog
Xenopus laevis
NP_001090534
393
43621
D274
L
P
V
I
P
V
L
D
I
D
F
A
C
D
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.2
93.1
20.6
N.A.
71.3
69.8
N.A.
46.1
23.9
34.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82.9
95
37.6
N.A.
81.3
80.3
N.A.
59.8
40.3
54.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
6.6
N.A.
20
13.3
N.A.
0
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
20
N.A.
26.6
26.6
N.A.
0
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
23
12
0
0
0
0
0
12
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
23
23
0
23
% C
% Asp:
0
0
0
0
0
0
0
23
0
12
0
12
0
12
56
% D
% Glu:
0
0
0
0
23
12
0
0
23
45
0
0
23
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
23
0
0
0
0
% F
% Gly:
0
0
34
0
12
0
0
0
45
12
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
23
0
0
0
23
12
0
0
0
0
12
0
% I
% Lys:
12
0
0
0
12
0
23
0
0
12
0
0
0
0
0
% K
% Leu:
34
0
0
12
12
0
45
0
0
0
0
34
23
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
45
12
34
12
34
34
12
0
0
12
23
34
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
0
0
0
34
0
% Q
% Arg:
0
12
0
0
23
0
0
0
0
0
0
0
0
23
0
% R
% Ser:
34
0
0
0
0
34
0
0
12
12
0
0
0
0
0
% S
% Thr:
0
12
12
0
0
0
0
45
0
0
0
0
0
0
12
% T
% Val:
12
0
23
23
0
12
0
0
0
0
12
0
0
12
0
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
56
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _