KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC1
All Species:
41.52
Human Site:
S104
Identified Species:
70.26
UniProt:
P07992
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07992
NP_001974.1
297
32562
S104
K
S
N
S
I
I
V
S
P
R
Q
R
G
N
P
Chimpanzee
Pan troglodytes
XP_001164747
297
32515
S104
K
S
N
S
I
I
V
S
P
R
Q
R
G
N
P
Rhesus Macaque
Macaca mulatta
XP_001105868
201
21761
S66
T
Y
A
E
Y
A
I
S
Q
P
P
G
G
A
G
Dog
Lupus familis
XP_855116
294
32368
S100
K
S
N
S
I
I
V
S
P
R
Q
R
G
N
P
Cat
Felis silvestris
Mouse
Mus musculus
P07903
298
32951
S104
K
S
N
S
I
I
V
S
P
R
Q
R
G
N
P
Rat
Rattus norvegicus
NP_001099698
298
32624
S104
K
S
S
S
I
I
V
S
P
R
Q
R
G
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517592
450
49542
S256
R
S
S
S
I
I
V
S
P
R
Q
R
G
N
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080498
289
32423
S103
A
G
S
C
I
L
V
S
T
R
Q
R
G
N
S
Zebra Danio
Brachydanio rerio
NP_001096608
342
37871
S145
S
G
N
S
I
I
V
S
P
R
Q
R
G
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623717
241
27330
D91
R
Y
H
Q
L
N
P
D
Y
I
H
E
R
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791729
471
51103
N263
S
G
N
S
V
I
V
N
P
R
Q
R
G
N
P
Poplar Tree
Populus trichocarpa
XP_002328427
382
43165
S100
S
R
N
A
I
L
V
S
H
R
Q
K
G
N
P
Maize
Zea mays
NP_001131279
397
43604
S113
S
K
N
S
I
L
V
S
H
R
Q
R
G
N
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MA98
410
45730
S129
N
R
N
A
I
L
V
S
H
R
Q
K
G
N
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
65.3
88.5
N.A.
86.2
83.5
N.A.
47.7
N.A.
51.8
52.9
N.A.
N.A.
44.7
N.A.
37.7
Protein Similarity:
100
99.6
66.3
91.2
N.A.
91.6
89.9
N.A.
56.4
N.A.
67
68.4
N.A.
N.A.
63.2
N.A.
48.4
P-Site Identity:
100
100
13.3
100
N.A.
100
93.3
N.A.
86.6
N.A.
53.3
86.6
N.A.
N.A.
0
N.A.
73.3
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
N.A.
66.6
86.6
N.A.
N.A.
20
N.A.
86.6
Percent
Protein Identity:
34.8
33
N.A.
33.4
N.A.
N.A.
Protein Similarity:
48.9
47.6
N.A.
47.3
N.A.
N.A.
P-Site Identity:
60
73.3
N.A.
60
N.A.
N.A.
P-Site Similarity:
80
80
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
15
0
8
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
22
0
0
0
0
0
0
0
0
0
8
93
0
8
% G
% His:
0
0
8
0
0
0
0
0
22
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
79
58
8
0
0
8
0
0
0
0
0
% I
% Lys:
36
8
0
0
0
0
0
0
0
0
0
15
0
0
8
% K
% Leu:
0
0
0
0
8
29
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
65
0
0
8
0
8
0
0
0
0
0
86
0
% N
% Pro:
0
0
0
0
0
0
8
0
58
8
8
0
0
0
79
% P
% Gln:
0
0
0
8
0
0
0
0
8
0
86
0
0
0
0
% Q
% Arg:
15
15
0
0
0
0
0
0
0
86
0
72
8
0
0
% R
% Ser:
29
43
22
65
0
0
0
86
0
0
0
0
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
86
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
8
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _