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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC1
All Species:
13.64
Human Site:
S14
Identified Species:
23.08
UniProt:
P07992
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07992
NP_001974.1
297
32562
S14
K
E
G
V
P
Q
P
S
G
P
P
A
R
K
K
Chimpanzee
Pan troglodytes
XP_001164747
297
32515
S14
K
E
G
V
P
Q
P
S
G
P
P
A
R
K
K
Rhesus Macaque
Macaca mulatta
XP_001105868
201
21761
Dog
Lupus familis
XP_855116
294
32368
A10
G
D
A
V
R
P
P
A
E
P
P
T
R
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P07903
298
32951
S14
E
E
S
R
P
Q
P
S
G
P
P
T
R
R
K
Rat
Rattus norvegicus
NP_001099698
298
32624
S14
E
E
N
R
P
Q
P
S
G
P
P
T
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517592
450
49542
A175
M
E
P
E
R
A
A
A
P
P
P
G
R
K
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080498
289
32423
F16
R
E
G
G
L
Q
R
F
L
I
P
S
P
S
S
Zebra Danio
Brachydanio rerio
NP_001096608
342
37871
G43
A
S
S
V
P
A
P
G
Q
P
L
S
Y
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623717
241
27330
V11
T
D
K
I
E
E
K
V
S
S
P
K
Q
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791729
471
51103
A146
R
E
R
L
E
A
G
A
A
A
P
T
L
Q
R
Poplar Tree
Populus trichocarpa
XP_002328427
382
43165
T12
E
R
G
E
E
Q
N
T
N
S
S
N
Q
N
K
Maize
Zea mays
NP_001131279
397
43604
A9
D
G
G
R
E
Q
Q
A
P
P
E
S
Q
P
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MA98
410
45730
I28
K
P
K
T
Q
I
V
I
G
V
P
S
Y
Q
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
65.3
88.5
N.A.
86.2
83.5
N.A.
47.7
N.A.
51.8
52.9
N.A.
N.A.
44.7
N.A.
37.7
Protein Similarity:
100
99.6
66.3
91.2
N.A.
91.6
89.9
N.A.
56.4
N.A.
67
68.4
N.A.
N.A.
63.2
N.A.
48.4
P-Site Identity:
100
100
0
46.6
N.A.
66.6
73.3
N.A.
33.3
N.A.
26.6
26.6
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
100
0
60
N.A.
80
80
N.A.
46.6
N.A.
40
40
N.A.
N.A.
40
N.A.
46.6
Percent
Protein Identity:
34.8
33
N.A.
33.4
N.A.
N.A.
Protein Similarity:
48.9
47.6
N.A.
47.3
N.A.
N.A.
P-Site Identity:
20
20
N.A.
20
N.A.
N.A.
P-Site Similarity:
40
40
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
22
8
29
8
8
0
15
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
22
50
0
15
29
8
0
0
8
0
8
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
8
36
8
0
0
8
8
36
0
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
8
0
8
0
0
0
8
0
% I
% Lys:
22
0
15
0
0
0
8
0
0
0
0
8
0
36
50
% K
% Leu:
0
0
0
8
8
0
0
0
8
0
8
0
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
8
0
0
8
0
8
0
% N
% Pro:
0
8
8
0
36
8
43
0
15
58
72
0
8
8
0
% P
% Gln:
0
0
0
0
8
50
8
0
8
0
0
0
22
15
0
% Q
% Arg:
15
8
8
22
15
0
8
0
0
0
0
0
43
8
15
% R
% Ser:
0
8
15
0
0
0
0
29
8
15
8
29
0
8
8
% S
% Thr:
8
0
0
8
0
0
0
8
0
0
0
29
0
0
0
% T
% Val:
0
0
0
29
0
0
8
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _