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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC1
All Species:
21.52
Human Site:
S159
Identified Species:
36.41
UniProt:
P07992
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07992
NP_001974.1
297
32562
S159
Y
I
H
G
R
L
Q
S
L
G
K
N
F
A
L
Chimpanzee
Pan troglodytes
XP_001164747
297
32515
S159
Y
I
H
G
R
L
Q
S
L
G
K
N
F
A
L
Rhesus Macaque
Macaca mulatta
XP_001105868
201
21761
N110
V
S
P
R
Q
R
G
N
P
V
L
K
F
V
R
Dog
Lupus familis
XP_855116
294
32368
S155
Y
I
H
E
R
L
Q
S
L
G
K
S
F
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P07903
298
32951
S159
Y
I
H
E
R
L
Q
S
L
G
K
N
F
A
L
Rat
Rattus norvegicus
NP_001099698
298
32624
S159
Y
I
H
E
R
L
Q
S
L
G
K
N
F
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517592
450
49542
G311
Y
I
H
E
R
L
Q
G
L
G
K
T
Y
Q
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080498
289
32423
S158
Y
I
H
S
R
L
R
S
L
G
Q
S
F
A
L
Zebra Danio
Brachydanio rerio
NP_001096608
342
37871
Q200
Y
V
H
E
R
L
K
Q
L
G
Q
S
F
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623717
241
27330
L136
C
I
L
A
D
L
T
L
M
L
A
W
N
P
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791729
471
51103
E318
Y
I
S
D
R
L
T
E
L
G
H
K
F
D
L
Poplar Tree
Populus trichocarpa
XP_002328427
382
43165
E155
Y
L
Y
Y
R
I
R
E
L
Q
K
N
C
K
L
Maize
Zea mays
NP_001131279
397
43604
E168
Y
L
Y
Y
R
I
R
E
L
Q
K
N
F
R
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MA98
410
45730
E184
Y
L
Y
F
R
I
R
E
L
Q
K
N
F
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
65.3
88.5
N.A.
86.2
83.5
N.A.
47.7
N.A.
51.8
52.9
N.A.
N.A.
44.7
N.A.
37.7
Protein Similarity:
100
99.6
66.3
91.2
N.A.
91.6
89.9
N.A.
56.4
N.A.
67
68.4
N.A.
N.A.
63.2
N.A.
48.4
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
93.3
N.A.
66.6
N.A.
73.3
53.3
N.A.
N.A.
13.3
N.A.
53.3
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
73.3
N.A.
93.3
86.6
N.A.
N.A.
20
N.A.
53.3
Percent
Protein Identity:
34.8
33
N.A.
33.4
N.A.
N.A.
Protein Similarity:
48.9
47.6
N.A.
47.3
N.A.
N.A.
P-Site Identity:
40
46.6
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
66.6
73.3
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
8
0
0
43
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
36
0
0
0
29
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
79
0
0
% F
% Gly:
0
0
0
15
0
0
8
8
0
65
0
0
0
0
0
% G
% His:
0
0
58
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
65
0
0
0
22
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
65
15
0
15
0
% K
% Leu:
0
22
8
0
0
72
0
8
86
8
8
0
0
0
86
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
50
8
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
43
8
0
22
15
0
0
8
0
% Q
% Arg:
0
0
0
8
86
8
29
0
0
0
0
0
0
8
8
% R
% Ser:
0
8
8
8
0
0
0
43
0
0
0
22
0
8
0
% S
% Thr:
0
0
0
0
0
0
15
0
0
0
0
8
0
0
0
% T
% Val:
8
8
0
0
0
0
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
86
0
22
15
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _