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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERCC1 All Species: 14.85
Human Site: S80 Identified Species: 25.13
UniProt: P07992 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07992 NP_001974.1 297 32562 S80 G A T C P T G S E P L A G E T
Chimpanzee Pan troglodytes XP_001164747 297 32515 S80 G A T C P T G S E P L A G E T
Rhesus Macaque Macaca mulatta XP_001105868 201 21761 S42 V A K P L F K S T Q S L P T V
Dog Lupus familis XP_855116 294 32368 P76 G A P H P T G P E P L T G E T
Cat Felis silvestris
Mouse Mus musculus P07903 298 32951 S80 G A T V P T G S E P A A G E N
Rat Rattus norvegicus NP_001099698 298 32624 S80 G A T V P T G S E P A T G D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517592 450 49542 G232 P V P D P S A G S T D G T P D
Chicken Gallus gallus
Frog Xenopus laevis NP_001080498 289 32423 A79 N M A A S E N A V S I V K Q T
Zebra Danio Brachydanio rerio NP_001096608 342 37871 G121 P T E D Q T K G E G Q S S E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623717 241 27330 I67 P W E Y S E I I P D Y V M G K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791729 471 51103 T239 Q A A V K Q S T S D S A V P G
Poplar Tree Populus trichocarpa XP_002328427 382 43165 K76 P P P P P P S K S E H G P S M
Maize Zea mays NP_001131279 397 43604 T89 P P P P P Q P T T T P R P T Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9MA98 410 45730 S105 H Q T D G A S S S S T P V A T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 65.3 88.5 N.A. 86.2 83.5 N.A. 47.7 N.A. 51.8 52.9 N.A. N.A. 44.7 N.A. 37.7
Protein Similarity: 100 99.6 66.3 91.2 N.A. 91.6 89.9 N.A. 56.4 N.A. 67 68.4 N.A. N.A. 63.2 N.A. 48.4
P-Site Identity: 100 100 13.3 73.3 N.A. 80 66.6 N.A. 6.6 N.A. 6.6 20 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 13.3 73.3 N.A. 80 80 N.A. 13.3 N.A. 26.6 33.3 N.A. N.A. 0 N.A. 20
Percent
Protein Identity: 34.8 33 N.A. 33.4 N.A. N.A.
Protein Similarity: 48.9 47.6 N.A. 47.3 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 20 N.A. N.A.
P-Site Similarity: 6.6 13.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 15 8 0 8 8 8 0 0 15 29 0 8 0 % A
% Cys: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 22 0 0 0 0 0 15 8 0 0 8 8 % D
% Glu: 0 0 15 0 0 15 0 0 43 8 0 0 0 36 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 36 0 0 0 8 0 36 15 0 8 0 15 36 8 8 % G
% His: 8 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 8 0 0 8 0 0 0 0 % I
% Lys: 0 0 8 0 8 0 15 8 0 0 0 0 8 0 8 % K
% Leu: 0 0 0 0 8 0 0 0 0 0 22 8 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 8 % M
% Asn: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % N
% Pro: 36 15 29 22 58 8 8 8 8 36 8 8 22 15 0 % P
% Gln: 8 8 0 0 8 15 0 0 0 8 8 0 0 8 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 0 0 0 15 8 22 43 29 15 15 8 8 8 15 % S
% Thr: 0 8 36 0 0 43 0 15 15 15 8 15 8 15 36 % T
% Val: 8 8 0 22 0 0 0 0 8 0 0 15 15 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _