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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS1
All Species:
21.82
Human Site:
S118
Identified Species:
48
UniProt:
P07996
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07996
NP_003237.2
1170
129383
S118
D
H
S
G
Q
V
F
S
V
V
S
N
G
K
A
Chimpanzee
Pan troglodytes
XP_510294
1457
160594
S405
D
H
S
G
Q
V
F
S
V
V
S
N
G
K
A
Rhesus Macaque
Macaca mulatta
XP_001093770
1444
157456
S392
D
H
S
G
Q
V
F
S
V
V
S
N
G
K
A
Dog
Lupus familis
XP_544610
1277
140508
S225
D
H
S
G
Q
V
F
S
V
V
S
N
G
R
A
Cat
Felis silvestris
Mouse
Mus musculus
P35441
1170
129629
S118
D
N
T
G
Q
I
F
S
V
V
S
N
G
K
A
Rat
Rattus norvegicus
P35444
755
82645
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521468
1253
138020
P91
G
G
P
G
R
E
D
P
S
G
E
R
G
A
T
Chicken
Gallus gallus
P35440
1178
131798
E120
G
I
S
E
R
Q
F
E
I
I
S
N
G
R
A
Frog
Xenopus laevis
P35448
1173
130001
S121
D
G
G
G
H
I
F
S
L
I
S
N
G
R
A
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
A21
V
L
M
S
V
W
S
A
Q
S
D
K
K
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783107
1328
146186
G125
G
H
T
D
R
L
F
G
L
V
I
D
R
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
80.4
89
N.A.
94.7
36.3
N.A.
67.7
62.7
80.4
36.9
N.A.
N.A.
N.A.
N.A.
44.1
Protein Similarity:
100
80.3
80.9
90.4
N.A.
97.8
45.7
N.A.
73.7
77.8
89.6
50.4
N.A.
N.A.
N.A.
N.A.
58.5
P-Site Identity:
100
100
100
93.3
N.A.
80
0
N.A.
13.3
40
53.3
0
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
20
66.6
80
13.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
64
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
55
0
0
10
0
0
10
0
0
0
10
10
0
0
10
% D
% Glu:
0
0
0
10
0
10
0
10
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% F
% Gly:
28
19
10
64
0
0
0
10
0
10
0
0
73
0
0
% G
% His:
0
46
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
19
0
0
10
19
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
10
46
0
% K
% Leu:
0
10
0
0
0
10
0
0
19
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
64
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
46
10
0
0
10
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
28
0
0
0
0
0
0
10
10
28
0
% R
% Ser:
0
0
46
10
0
0
10
55
10
10
64
0
0
0
10
% S
% Thr:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
10
0
0
0
10
37
0
0
46
55
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _