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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS1
All Species:
29.09
Human Site:
S405
Identified Species:
64
UniProt:
P07996
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07996
NP_003237.2
1170
129383
S405
G
I
Q
Q
R
G
R
S
C
D
S
L
N
N
R
Chimpanzee
Pan troglodytes
XP_510294
1457
160594
S692
G
I
Q
Q
R
G
R
S
C
D
S
L
N
N
R
Rhesus Macaque
Macaca mulatta
XP_001093770
1444
157456
S679
G
I
Q
Q
R
G
R
S
C
D
S
L
N
N
R
Dog
Lupus familis
XP_544610
1277
140508
S512
G
I
Q
Q
R
G
R
S
C
D
S
L
N
N
R
Cat
Felis silvestris
Mouse
Mus musculus
P35441
1170
129629
S405
G
I
Q
Q
R
G
R
S
C
D
S
L
N
N
R
Rat
Rattus norvegicus
P35444
755
82645
V83
A
R
T
P
G
L
S
V
R
P
V
A
L
C
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521468
1253
138020
I369
W
S
P
W
S
V
W
I
T
C
S
A
S
L
P
Chicken
Gallus gallus
P35440
1178
131798
S413
G
T
Q
M
R
G
R
S
C
D
V
T
R
S
A
Frog
Xenopus laevis
P35448
1173
130001
S408
G
I
Q
Q
R
G
R
S
C
D
S
L
N
N
P
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
S291
N
P
C
F
K
G
V
S
C
M
E
T
F
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783107
1328
146186
S533
G
T
M
Q
R
G
R
S
C
D
R
M
R
Y
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
80.4
89
N.A.
94.7
36.3
N.A.
67.7
62.7
80.4
36.9
N.A.
N.A.
N.A.
N.A.
44.1
Protein Similarity:
100
80.3
80.9
90.4
N.A.
97.8
45.7
N.A.
73.7
77.8
89.6
50.4
N.A.
N.A.
N.A.
N.A.
58.5
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
6.6
53.3
93.3
20
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
13.3
60
93.3
26.6
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
19
0
0
19
% A
% Cys:
0
0
10
0
0
0
0
0
82
10
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
73
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
73
0
0
0
10
82
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
55
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
55
10
10
0
% L
% Met:
0
0
10
10
0
0
0
0
0
10
0
10
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
55
55
0
% N
% Pro:
0
10
10
10
0
0
0
0
0
10
0
0
0
0
28
% P
% Gln:
0
0
64
64
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
73
0
73
0
10
0
10
0
19
0
46
% R
% Ser:
0
10
0
0
10
0
10
82
0
0
64
0
10
10
0
% S
% Thr:
0
19
10
0
0
0
0
0
10
0
0
19
0
0
0
% T
% Val:
0
0
0
0
0
10
10
10
0
0
19
0
0
0
0
% V
% Trp:
10
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _