KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS1
All Species:
26.06
Human Site:
S56
Identified Species:
57.33
UniProt:
P07996
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07996
NP_003237.2
1170
129383
S56
V
K
G
P
D
P
S
S
P
A
F
R
I
E
D
Chimpanzee
Pan troglodytes
XP_510294
1457
160594
S343
V
K
G
P
D
P
S
S
P
A
F
R
I
E
D
Rhesus Macaque
Macaca mulatta
XP_001093770
1444
157456
S330
V
K
G
P
D
P
S
S
P
A
F
R
I
E
D
Dog
Lupus familis
XP_544610
1277
140508
S163
V
K
G
P
D
P
S
S
P
A
F
R
I
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P35441
1170
129629
S56
V
K
G
Q
D
L
S
S
P
A
F
R
I
E
N
Rat
Rattus norvegicus
P35444
755
82645
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521468
1253
138020
S47
P
V
E
T
D
L
P
S
V
T
A
L
R
H
L
Chicken
Gallus gallus
P35440
1178
131798
I58
F
R
G
P
D
P
A
I
P
A
Y
R
F
I
R
Frog
Xenopus laevis
P35448
1173
130001
S59
V
K
G
P
D
P
S
S
P
A
Y
R
I
E
D
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783107
1328
146186
S63
V
R
G
Q
E
E
N
S
V
A
Y
K
I
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
80.4
89
N.A.
94.7
36.3
N.A.
67.7
62.7
80.4
36.9
N.A.
N.A.
N.A.
N.A.
44.1
Protein Similarity:
100
80.3
80.9
90.4
N.A.
97.8
45.7
N.A.
73.7
77.8
89.6
50.4
N.A.
N.A.
N.A.
N.A.
58.5
P-Site Identity:
100
100
100
100
N.A.
80
0
N.A.
13.3
46.6
93.3
0
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
0
N.A.
13.3
66.6
100
0
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
73
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
73
0
0
0
0
0
0
0
0
0
46
% D
% Glu:
0
0
10
0
10
10
0
0
0
0
0
0
0
55
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
46
0
10
0
0
% F
% Gly:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
64
10
0
% I
% Lys:
0
55
0
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
0
0
0
19
0
0
0
0
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
10
0
0
55
0
55
10
0
64
0
0
0
0
0
10
% P
% Gln:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
19
0
0
0
0
0
0
0
0
0
64
10
0
10
% R
% Ser:
0
0
0
0
0
0
55
73
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
64
10
0
0
0
0
0
0
19
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
28
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _