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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS1
All Species:
34.55
Human Site:
S921
Identified Species:
76
UniProt:
P07996
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07996
NP_003237.2
1170
129383
S921
P
N
P
D
Q
K
D
S
D
G
D
G
R
G
D
Chimpanzee
Pan troglodytes
XP_510294
1457
160594
S1208
P
N
P
D
Q
K
D
S
D
G
D
G
R
G
D
Rhesus Macaque
Macaca mulatta
XP_001093770
1444
157456
S1195
P
N
P
D
Q
K
D
S
D
G
D
G
R
G
D
Dog
Lupus familis
XP_544610
1277
140508
S1028
P
N
P
D
Q
K
D
S
D
G
D
G
R
G
D
Cat
Felis silvestris
Mouse
Mus musculus
P35441
1170
129629
S921
P
N
P
D
Q
K
D
S
D
G
D
G
R
G
D
Rat
Rattus norvegicus
P35444
755
82645
I512
D
F
D
A
D
K
V
I
D
K
I
D
V
C
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521468
1253
138020
S886
P
N
P
D
Q
K
D
S
D
G
D
G
R
G
D
Chicken
Gallus gallus
P35440
1178
131798
S929
Y
N
P
E
Q
E
D
S
D
G
D
G
R
G
D
Frog
Xenopus laevis
P35448
1173
130001
T924
P
N
P
D
Q
T
D
T
N
G
D
G
R
G
D
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
V719
S
V
M
D
L
V
D
V
C
P
E
S
A
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783107
1328
146186
T1051
F
N
P
S
Q
N
D
T
D
E
N
G
R
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
80.4
89
N.A.
94.7
36.3
N.A.
67.7
62.7
80.4
36.9
N.A.
N.A.
N.A.
N.A.
44.1
Protein Similarity:
100
80.3
80.9
90.4
N.A.
97.8
45.7
N.A.
73.7
77.8
89.6
50.4
N.A.
N.A.
N.A.
N.A.
58.5
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
100
80
80
13.3
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
93.3
93.3
20
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% C
% Asp:
10
0
10
73
10
0
91
0
82
0
73
10
0
0
82
% D
% Glu:
0
0
0
10
0
10
0
0
0
10
10
0
0
10
0
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
73
0
82
0
82
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
64
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
82
0
0
0
10
0
0
10
0
10
0
0
0
0
% N
% Pro:
64
0
82
0
0
0
0
0
0
10
0
0
0
0
10
% P
% Gln:
0
0
0
0
82
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% R
% Ser:
10
0
0
10
0
0
0
64
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
19
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
10
10
10
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _