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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS1
All Species:
36.67
Human Site:
Y1022
Identified Species:
80.67
UniProt:
P07996
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07996
NP_003237.2
1170
129383
Y1022
N
T
E
R
D
D
D
Y
A
G
F
V
F
G
Y
Chimpanzee
Pan troglodytes
XP_510294
1457
160594
Y1309
N
T
E
R
D
D
D
Y
A
G
F
V
F
G
Y
Rhesus Macaque
Macaca mulatta
XP_001093770
1444
157456
Y1296
N
T
E
R
D
D
D
Y
A
G
F
V
F
G
Y
Dog
Lupus familis
XP_544610
1277
140508
Y1129
N
T
E
R
D
D
D
Y
A
G
F
V
F
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
P35441
1170
129629
Y1022
N
T
E
R
D
D
D
Y
A
G
F
V
F
G
Y
Rat
Rattus norvegicus
P35444
755
82645
Y608
Y
Q
D
S
S
S
F
Y
V
V
M
W
K
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521468
1253
138020
Y987
N
T
E
R
D
D
D
Y
A
G
F
V
F
G
Y
Chicken
Gallus gallus
P35440
1178
131798
Y1030
N
T
D
R
D
D
D
Y
A
G
F
V
F
G
Y
Frog
Xenopus laevis
P35448
1173
130001
Y1025
N
T
E
R
D
D
D
Y
A
G
F
V
F
G
Y
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
K815
S
F
Y
V
V
M
W
K
Q
T
E
Q
T
Y
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783107
1328
146186
Y1152
N
T
A
K
D
D
D
Y
A
G
F
I
F
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
80.4
89
N.A.
94.7
36.3
N.A.
67.7
62.7
80.4
36.9
N.A.
N.A.
N.A.
N.A.
44.1
Protein Similarity:
100
80.3
80.9
90.4
N.A.
97.8
45.7
N.A.
73.7
77.8
89.6
50.4
N.A.
N.A.
N.A.
N.A.
58.5
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
93.3
100
0
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
100
13.3
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
82
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
82
82
82
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
64
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
10
0
0
0
82
0
82
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
82
0
0
0
82
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
10
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
10
% M
% Asn:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
0
10
0
10
0
% Q
% Arg:
0
0
0
73
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
82
0
0
0
0
0
0
0
10
0
0
10
0
0
% T
% Val:
0
0
0
10
10
0
0
0
10
10
0
73
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% W
% Tyr:
10
0
10
0
0
0
0
91
0
0
0
0
0
10
82
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _