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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GJB1
All Species:
9.09
Human Site:
T269
Identified Species:
22.22
UniProt:
P08034
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08034
NP_000157.1
283
32025
T269
I
L
R
R
S
P
G
T
G
A
G
L
A
E
K
Chimpanzee
Pan troglodytes
XP_001145895
209
24152
L196
N
V
T
E
L
C
Y
L
L
I
R
Y
C
S
G
Rhesus Macaque
Macaca mulatta
Q8MIT8
226
26206
L213
N
V
T
E
L
C
Y
L
L
I
R
Y
C
S
G
Dog
Lupus familis
XP_538073
283
31973
T269
I
L
R
R
S
P
G
T
G
A
G
L
A
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P70689
261
30348
E243
L
K
E
S
K
Q
N
E
M
N
E
L
I
S
D
Rat
Rattus norvegicus
P08033
283
31985
T269
I
L
R
R
S
P
G
T
G
A
G
L
A
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519735
229
25750
G216
D
L
L
R
R
G
P
G
S
A
P
A
E
K
G
Chicken
Gallus gallus
O93533
263
30905
E247
T
K
Q
N
E
M
N
E
L
I
S
D
S
C
Q
Frog
Xenopus laevis
P08983
264
29977
K250
I
T
G
G
S
I
I
K
R
S
A
G
Q
E
K
Zebra Danio
Brachydanio rerio
O57474
381
43436
L288
M
S
P
P
G
Y
K
L
A
T
G
E
R
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.5
52.6
98.5
N.A.
54.4
98.5
N.A.
69.9
54.7
69.9
36.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
64.6
67.8
98.9
N.A.
71.7
99.2
N.A.
74.5
71
80.2
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
100
N.A.
6.6
100
N.A.
20
0
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
6.6
100
N.A.
13.3
100
N.A.
26.6
20
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
40
10
10
30
0
0
% A
% Cys:
0
0
0
0
0
20
0
0
0
0
0
0
20
10
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% D
% Glu:
0
0
10
20
10
0
0
20
0
0
10
10
10
40
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
10
10
30
10
30
0
40
10
0
0
30
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
40
0
0
0
0
10
10
0
0
30
0
0
10
0
0
% I
% Lys:
0
20
0
0
10
0
10
10
0
0
0
0
0
10
40
% K
% Leu:
10
40
10
0
20
0
0
30
30
0
0
40
0
0
0
% L
% Met:
10
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
20
0
0
10
0
0
20
0
0
10
0
0
0
0
10
% N
% Pro:
0
0
10
10
0
30
10
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
10
0
0
10
0
0
0
0
0
0
10
0
10
% Q
% Arg:
0
0
30
40
10
0
0
0
10
0
20
0
10
0
0
% R
% Ser:
0
10
0
10
40
0
0
0
10
10
10
0
10
30
0
% S
% Thr:
10
10
20
0
0
0
0
30
0
10
0
0
0
10
0
% T
% Val:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
20
0
0
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _