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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPA1A All Species: 46.97
Human Site: S385 Identified Species: 93.94
UniProt: P08107 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08107 NP_005336.3 641 70052 S385 A I L M G D K S E N V Q D L L
Chimpanzee Pan troglodytes XP_527345 641 70451 S387 A I L M G D K S E K V Q D L L
Rhesus Macaque Macaca mulatta XP_001113329 641 70349 S387 A I L M G D K S E K V Q D L L
Dog Lupus familis XP_532082 641 70502 S387 A I L M G D K S E K V Q D L L
Cat Felis silvestris
Mouse Mus musculus Q61696 641 70061 S385 A I L M G D K S E N V Q D L L
Rat Rattus norvegicus Q07439 641 70167 S385 A I L M G D K S E N V Q D L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510204 645 70485 S387 A I L M G D R S E K V Q D L L
Chicken Gallus gallus O73885 646 70808 S385 A I L S G D K S E N V Q D L L
Frog Xenopus laevis P02827 647 70897 S386 A I L M G D K S E N V Q D L L
Zebra Danio Brachydanio rerio Q90473 649 70955 S385 A I L S G D K S E N V Q D L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11147 651 71113 S385 A I L H G D K S Q E V Q D L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P09446 640 69704 S386 A I L S G D K S E A V Q D L L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.5 90.1 89.8 N.A. 95.3 96.5 N.A. 88 84.8 85.4 84.5 N.A. 81.5 N.A. 82.5 N.A.
Protein Similarity: 100 94.3 95 95.1 N.A. 98.4 98.5 N.A. 95.1 92.2 93.3 91.3 N.A. 90 N.A. 90.6 N.A.
P-Site Identity: 100 93.3 93.3 93.3 N.A. 100 100 N.A. 86.6 93.3 100 93.3 N.A. 80 N.A. 86.6 N.A.
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 100 100 N.A. 93.3 93.3 100 93.3 N.A. 86.6 N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 100 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 100 0 0 0 0 0 0 100 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 92 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 92 0 0 34 0 0 0 0 0 % K
% Leu: 0 0 100 0 0 0 0 0 0 0 0 0 0 100 100 % L
% Met: 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 0 100 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 25 0 0 0 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _