KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA1A
All Species:
36.36
Human Site:
Y611
Identified Species:
72.73
UniProt:
P08107
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08107
NP_005336.3
641
70052
Y611
N
P
I
I
S
G
L
Y
Q
G
A
G
G
P
G
Chimpanzee
Pan troglodytes
XP_527345
641
70451
Y613
N
P
I
I
T
K
L
Y
Q
G
G
C
T
G
P
Rhesus Macaque
Macaca mulatta
XP_001113329
641
70349
Y613
N
P
I
I
T
K
L
Y
Q
G
G
C
T
G
P
Dog
Lupus familis
XP_532082
641
70502
Y613
N
P
V
I
T
K
L
Y
Q
G
G
C
T
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61696
641
70061
Y611
S
P
I
I
S
G
L
Y
Q
G
A
G
A
P
G
Rat
Rattus norvegicus
Q07439
641
70167
Y611
N
P
I
I
S
G
L
Y
Q
G
A
G
A
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510204
645
70485
Y615
H
P
I
V
T
R
L
Y
Q
G
E
G
A
A
G
Chicken
Gallus gallus
O73885
646
70808
Y611
N
P
I
I
T
K
L
Y
Q
S
A
G
G
M
P
Frog
Xenopus laevis
P02827
647
70897
Y612
Q
P
I
I
T
K
L
Y
Q
G
G
V
P
G
G
Zebra Danio
Brachydanio rerio
Q90473
649
70955
Y611
N
P
I
I
T
K
L
Y
Q
S
A
G
G
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11147
651
71113
Y611
N
P
I
I
T
K
L
Y
Q
G
A
G
F
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P09446
640
69704
Y612
N
P
I
I
S
K
L
Y
Q
S
A
G
G
A
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
90.1
89.8
N.A.
95.3
96.5
N.A.
88
84.8
85.4
84.5
N.A.
81.5
N.A.
82.5
N.A.
Protein Similarity:
100
94.3
95
95.1
N.A.
98.4
98.5
N.A.
95.1
92.2
93.3
91.3
N.A.
90
N.A.
90.6
N.A.
P-Site Identity:
100
53.3
53.3
46.6
N.A.
86.6
93.3
N.A.
53.3
66.6
53.3
66.6
N.A.
73.3
N.A.
73.3
N.A.
P-Site Similarity:
100
60
60
60
N.A.
93.3
93.3
N.A.
73.3
73.3
60
73.3
N.A.
80
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
59
0
25
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
25
0
0
0
75
34
67
34
34
42
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
92
92
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% M
% Asn:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
100
0
0
0
0
0
0
0
0
0
0
9
34
59
% P
% Gln:
9
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
34
0
0
0
0
25
0
0
0
0
0
% S
% Thr:
0
0
0
0
67
0
0
0
0
0
0
0
25
0
0
% T
% Val:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _