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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANXA6
All Species:
18.79
Human Site:
S537
Identified Species:
45.93
UniProt:
P08133
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08133
NP_001146.2
673
75873
S537
L
E
I
A
D
T
P
S
G
D
K
T
S
L
E
Chimpanzee
Pan troglodytes
A5A6L7
327
36886
M199
K
I
R
G
T
D
E
M
K
F
I
T
I
L
C
Rhesus Macaque
Macaca mulatta
XP_001100437
712
80479
S576
L
E
I
A
D
T
P
S
G
D
K
A
S
L
E
Dog
Lupus familis
XP_853454
672
75871
S536
L
E
I
A
D
T
P
S
G
D
K
T
S
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P14824
673
75868
S537
L
E
I
A
D
T
P
S
G
D
K
T
S
L
E
Rat
Rattus norvegicus
P48037
673
75736
S537
L
E
I
A
D
T
P
S
G
D
K
T
S
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507126
543
60359
A415
I
L
T
H
R
S
N
A
Q
R
Q
E
I
R
K
Chicken
Gallus gallus
P51901
671
75200
N536
K
L
A
D
V
P
S
N
D
S
S
D
S
L
E
Frog
Xenopus laevis
P24801
340
38756
T212
K
R
K
G
T
D
V
T
K
W
I
T
I
M
T
Zebra Danio
Brachydanio rerio
XP_002664532
596
67301
I468
L
E
D
K
F
M
S
I
L
C
T
R
S
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26
90.1
95.9
N.A.
94.5
94.5
N.A.
59.8
78.7
26.4
62.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
36.2
91.8
98
N.A.
97
97.1
N.A.
66.7
89.7
39
74.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
100
N.A.
100
100
N.A.
0
20
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
100
N.A.
100
100
N.A.
33.3
26.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
50
0
0
0
10
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% C
% Asp:
0
0
10
10
50
20
0
0
10
50
0
10
0
0
0
% D
% Glu:
0
60
0
0
0
0
10
0
0
0
0
10
0
0
60
% E
% Phe:
0
0
0
0
10
0
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
0
0
20
0
0
0
0
50
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
50
0
0
0
0
10
0
0
20
0
30
0
0
% I
% Lys:
30
0
10
10
0
0
0
0
20
0
50
0
0
0
10
% K
% Leu:
60
20
0
0
0
0
0
0
10
0
0
0
0
70
0
% L
% Met:
0
0
0
0
0
10
0
10
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
50
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
10
10
0
10
0
0
0
0
10
0
10
0
10
0
% R
% Ser:
0
0
0
0
0
10
20
50
0
10
10
0
70
0
0
% S
% Thr:
0
0
10
0
20
50
0
10
0
0
10
60
0
0
10
% T
% Val:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _