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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NGFR All Species: 26.36
Human Site: S416 Identified Species: 58
UniProt: P08138 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08138 NP_002498.1 427 45183 S416 Q R A D L V E S L C S E S T A
Chimpanzee Pan troglodytes XP_511950 427 45135 S416 Q R A D L V E S L C S E S T A
Rhesus Macaque Macaca mulatta XP_001090039 523 55898 S512 Q R A D L V E S L C S E S T A
Dog Lupus familis XP_548191 407 43351 S396 Q R A D I V E S L C S E S T A
Cat Felis silvestris
Mouse Mus musculus Q9Z0W1 417 44667 S406 Q R A D I V E S L C S E S T A
Rat Rattus norvegicus P07174 425 45414 S414 Q R A D I V E S L C S E S T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520448 431 46388 N420 Q R G D I A E N L Y S D S T A
Chicken Gallus gallus P18519 416 44636 S405 Q R G D I A E S L Y S E S T A
Frog Xenopus laevis NP_001081935 401 43401 L391 R D D I A Q S L N S D S T A T
Zebra Danio Brachydanio rerio XP_002663962 396 43002 I386 R E D I A Q S I I V K P T A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780520 410 45015 P400 E H L I Q D T P P Q S R K L M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 80.6 91.5 N.A. 90.4 92 N.A. 71 70.2 55.7 48.7 N.A. N.A. N.A. N.A. 20.8
Protein Similarity: 100 99.7 80.6 93.6 N.A. 92 93.6 N.A. 78.4 80.5 69 63.4 N.A. N.A. N.A. N.A. 34.6
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 60 73.3 0 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 80 80 13.3 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 55 0 19 19 0 0 0 0 0 0 0 19 73 % A
% Cys: 0 0 0 0 0 0 0 0 0 55 0 0 0 0 0 % C
% Asp: 0 10 19 73 0 10 0 0 0 0 10 10 0 0 0 % D
% Glu: 10 10 0 0 0 0 73 0 0 0 0 64 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 28 46 0 0 10 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % K
% Leu: 0 0 10 0 28 0 0 10 73 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 10 0 0 10 0 0 0 % P
% Gln: 73 0 0 0 10 19 0 0 0 10 0 0 0 0 0 % Q
% Arg: 19 73 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 0 0 0 19 64 0 10 82 10 73 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 19 73 19 % T
% Val: 0 0 0 0 0 55 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _