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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GLI1
All Species:
24.55
Human Site:
S457
Identified Species:
54
UniProt:
P08151
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08151
NP_005260.1
1106
117904
S457
S
D
H
S
P
A
G
S
A
A
N
T
D
S
G
Chimpanzee
Pan troglodytes
Q5IS56
1580
169881
I720
C
S
S
Q
Q
S
P
I
S
N
Y
S
N
S
G
Rhesus Macaque
Macaca mulatta
XP_001116072
1106
117669
S457
S
D
H
S
P
A
G
S
A
A
N
T
D
S
G
Dog
Lupus familis
XP_538247
1105
117188
S456
S
D
H
S
P
A
G
S
A
A
N
T
D
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P47806
1111
118537
S459
S
D
H
S
P
A
G
S
A
A
N
T
D
S
G
Rat
Rattus norvegicus
XP_345833
1109
118200
S456
S
D
H
S
P
A
G
S
A
A
N
T
D
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506723
1591
170747
I721
C
S
S
E
Q
S
P
I
S
H
Y
S
N
S
G
Chicken
Gallus gallus
P55878
556
60197
Frog
Xenopus laevis
Q91690
1360
149404
S480
S
E
R
S
P
L
G
S
T
N
N
N
D
S
G
Zebra Danio
Brachydanio rerio
NP_840081
1404
152814
S526
S
E
R
S
P
L
G
S
A
N
N
N
D
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19538
1397
153262
V678
N
H
H
L
V
N
G
V
R
A
S
D
S
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
96.8
91.1
N.A.
85.5
85.8
N.A.
32.5
33.6
40.5
39.6
N.A.
23.9
N.A.
N.A.
N.A.
Protein Similarity:
100
42.1
97.6
93.4
N.A.
89.1
89.5
N.A.
42.5
39.4
54.1
51.4
N.A.
37.9
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
13.3
0
60
66.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
40
0
66.6
73.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
46
0
0
55
55
0
0
0
0
0
% A
% Cys:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
0
0
0
0
0
0
0
0
0
10
64
0
0
% D
% Glu:
0
19
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
73
0
0
0
0
0
0
0
82
% G
% His:
0
10
55
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
19
0
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
10
0
0
0
28
64
19
19
0
0
% N
% Pro:
0
0
0
0
64
0
19
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
19
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
64
19
19
64
0
19
0
64
19
0
10
19
10
82
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
46
0
0
0
% T
% Val:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _